DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ir87a and glr-8

DIOPT Version :9

Sequence 1:NP_650290.2 Gene:Ir87a / 41654 FlyBaseID:FBgn0038153 Length:796 Species:Drosophila melanogaster
Sequence 2:NP_001368711.1 Gene:glr-8 / 180924 WormBaseID:WBGene00001619 Length:547 Species:Caenorhabditis elegans


Alignment Length:451 Identity:95/451 - (21%)
Similarity:169/451 - (37%) Gaps:78/451 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   376 NYGESDDESYADPGEDGDGAIPDTETQSGGKLKLSGIEYEMVQTIAERLHVSIEMQGE--NSNLY 438
            ||....|.:..|.|. |.|.:.:...:.|.:|.|:   ||::..:.       ...||  |.:..
 Worm    77 NYVNFSDAAVTDKGY-GPGVVMEILKEIGKRLNLT---YEILPALG-------STWGEYLNGSWT 130

  Fly   439 HLFQQLIDGEIEMIVGGIDEDPSISQFVSSSIPYHQDELTWCVARAKRRHGF---------FNFV 494
            ..|.||:.||::::.||...:...|.....:.|: |.|.|..:.|:..::..         |::.
 Worm   131 GAFGQLVRGEVDLLAGGAIMEYDRSVIADLTYPF-QFEPTGIMIRSPEKYEDDTLLIVTEPFSWE 194

  Fly   495 ATFNADAGFLIG--IFVVTCSLVVWLAQRVSGFQLRNLNGYFPTCLRVLGILLNQAIPAQDFPIT 557
            ......|..||.  ||:|..:::..:.:.::.....::..:|       .|.:.|.:|.|....:
 Worm   195 VWVITAAVILISGVIFLVMTNIIRKVYEEMTVTPFESIWVFF-------SIFVQQGLPEQPRSWS 252

  Fly   558 LRQLFALSFLMGFFFSNTYQSFLISTLTTPRSSYQIHTLQEIYSNKMTVMGTSEHVRHLNKDGEI 622
            .|.|.||.:|.....|.|:...|::.....:::.....:.::.  ::...|..|.|...|.....
 Worm   253 CRVLVALWWLASITLSATFTGSLVALFAVDKTNVPFQNIDQLV--RLVKQGKFEIVMDENSFTRT 315

  Fly   623 FKYIREKFQMCYNL---------VDCLNDAAQNEHIAVAVSRQHSFY---NPRIQRDRLYCFDRR 675
            ....|.|..:..:|         |..:|..|:    .||..|.:..|   .|....:.....|.:
 Worm   316 EMIARSKLPVYRDLWHEMIVNHKVKYVNGIAR----GVAFVRANPGYALLGPMATLNFYAYSDCK 376

  Fly   676 ESLY------VYLVTMLLPKKYHLLHQINPVIQHIIESGHMQKWARD----LDMRRMIHEEITRV 730
            ..|:      |||...|:....:..: .:..|:.::|.|..|||..|    :.|:::  .|....
 Worm   377 VILFNDGILPVYLSIPLVKNSIYSPY-FSTKIREMVERGFTQKWIADYRSYVAMQKI--NECNST 438

  Fly   731 REDPFKALTFDQFRGAI-AFSGG-----LLLVASCVFAFELCYVKYVYRTEKRERKTKKIT 785
            ...|...|...:.:||. .|.||     .|.|...:|.|        :| ||..:.||..|
 Worm   439 TIGPKSYLDLKRAQGAFWVFLGGAGLGLALFVGEFIFKF--------FR-EKMTKHTKTTT 490

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir87aNP_650290.2 Periplasmic_Binding_Protein_Type_2 408..>475 CDD:304360 15/68 (22%)
glr-8NP_001368711.1 PBP2_iGluR_ligand_binding 62..424 CDD:270219 76/372 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR42643
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

Return to query results.
Submit another query.