DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir87a and grik4

DIOPT Version :9

Sequence 1:	NP_650290.2	Gene:	Ir87a / 41654	FlyBaseID:	FBgn0038153	Length:	796	Species:	Drosophila melanogaster
Sequence 2:	XP_031761990.1	Gene:	grik4 / 100490768	XenbaseID:	XB-GENE-1011875	Length:	962	Species:	Xenopus tropicalis

Alignment Length:	294	Identity:	48/294 - (16%)
Similarity:	109/294 - (37%)	Gaps:	52/294 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   405 GKLKLSGIEYEMVQTIAE--RLHVSIEMQGE--------NSNLYHLFQQLIDGEIEMIVGGIDED 459
            |..:..|...:|::.:|.  |.:..|.:..:        |.....:..:||..:.::.|.|:...
Frog   443 GNDRYEGFCVDMLKELAAILRFNYKIRLVADGVYGVPELNGTWTGMVGELISRKADLAVAGLTIT 507

  Fly   460 PSISQFVSSSIPYHQDELTWCVARAKRRH-----GFFNFVATFNADAGFLIGIFVVTCSLVVWLA 519
            ....:.:..|.|:    :|..::...|.|     |:|:|:..|:......:.:..:..|.|::|.
Frog   508 AEREKVIDFSKPF----MTLGISILYRVHMGRKPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLV 568

  Fly   520 QRVSGFQLRN------------LNGY-------FPTCLRVLGILLNQAIPAQDFPITLRQLFALS 565
            .|::.::..:            :|.|       ||     :|..:.|........::.|.:..:.
Frog   569 ARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFP-----VGGFMQQGSTIAPRALSTRCVSGVW 628

  Fly   566 FLMGFFFSNTYQSFLISTLTTPRSSYQIHTLQEIYSNKMTVMGTSEHVRHLNKDGEIFKYIR-EK 629
            :.......::|.:.|.:.||..|....|.::.::........||.    |.......|:..| :.
Frog   629 WAFTLIIISSYTANLAAFLTVQRMDVPIESVDDLADQTTIEYGTI----HGGSSMTFFQNSRYQT 689

  Fly   630 FQMCYNLVDCLNDA----AQNEHIAVAVSRQHSF 659
            :|..:|.:.....:    :..|.||..::..::|
Frog   690 YQRMWNYMHSKQPSVFVKSTEEGIARVLNSNYAF 723

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir87a	NP_650290.2	Periplasmic_Binding_Protein_Type_2	408..>475	CDD:304360	12/76 (16%)
grik4	XP_031761990.1	Periplasmic_Binding_Protein_type1	23..400	CDD:415822
grik4	XP_031761990.1	PBP2_iGluR_kainate_KA1	414..788	CDD:270442	48/294 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910