DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment yellow-e and YBR053C

DIOPT Version :9

Sequence 1:	NP_524344.1	Gene:	yellow-e / 41653	FlyBaseID:	FBgn0041711	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_009609.1	Gene:	YBR053C / 852342	SGDID:	S000000257	Length:	358	Species:	Saccharomyces cerevisiae

Alignment Length:	197	Identity:	44/197 - (22%)
Similarity:	72/197 - (36%)	Gaps:	49/197 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   216 GKDVTWRVSHPAMYPDPD---------------FAQSEIHEHRFVLMDGVVGLTFDERTG---VV 262
            ||:.:  :.:|   |:||               .:|:||.:..|....|:..|.|.:...   ::
Yeast    73 GKNAS--IEYP---PNPDELKESVGCIFPILDGASQNEIKQVLFGSKFGIGKLDFSKSEWEYVIL 132

  Fly   263 YFQ--PLATDRVFSVHKNVLRAGPLPDGKMLDVKLVGKKSSQGIGLAVSPFDSSLIFSPLSETAI 325
            |.:  .|:|||.:.:..|  .....||||.:.|.|          ::..|||...|...|....:
Yeast   133 YSECPELSTDRAYKLRSN--DGNVSPDGKYIYVGL----------MSDFPFDLEPIGCLLRVDLL 185

  Fly   326 AS-----WNPTTNQQSVLAFDRDQ-LQFVAD---ITTTKSEPGVIYAIASKFHRFFLKNLNPNEF 381
            |.     ||......::...:.|| ..:|.|   .|..|...|   .:..:.....:||.|...|
Yeast   186 AHKIELVWNCLLIPNAIHWDESDQKTMYVTDSLNFTIWKCPGG---DLLKRDELIDVKNSNNQSF 247

  Fly   382 NN 383
            .:
Yeast   248 ES 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yellow-e	NP_524344.1	MRJP	120..393	CDD:281074	44/197 (22%)
YBR053C	NP_009609.1	YvrE	1..345	CDD:225921	44/197 (22%)
		WD40 repeat	150..186	CDD:293791	12/47 (26%)
		WD40 repeat	199..248	CDD:293791	10/51 (20%)
		WD40 repeat	259..294	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3386
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900