Protein Alignment CG9799 and Y45F10D.7

DIOPT Version :10

• Sequence 1: NP_650284.2
• Gene: CG9799 / 41647
• FlyBaseID: FBgn0038146
• Length: 922
• Species: Drosophila melanogaster
• Sequence 2: NP_001369795.1
• Gene: Y45F10D.7 / 178346
• WormBaseID: WBGene00012887
• Length: 924
• Species: Caenorhabditis elegans
• Alignment Length: 970
• Identity: 301/970 - (31%)
• Similarity: 480/970 - (49%)
• Gaps: 131/970 - (13%)

  Fly    25 IFRRNRALGYVSNQV-PAVTRYVQRRRDTLLITC-IGRSFQVYTANHFRLLHVSGLHPDEITALA 87
            :|...|.||.|:..| |::......::..|.:.| |......|.....|.:.:|....|:::|:|
 Worm     8 LFAPYRFLGVVTGDVAPSIRSTFVAKKSALSVLCPIDNVIMQYNGKKLRAIGMSEPLSDKVSAVA 72

  Fly    88 TDRLHTYTASNKCIYAWRAGKHIRHVYRGHQKD-------VHLLLPFGSSLIAIDRQNVLKVWNI 145
            :.....:.|....|.:....:.|        ||       :.::...|:.|||:|..:.:.|  |
 Worm    73 SSSTSVFAAHGTNITSLAFCRDI--------KDSIDLGAKIKIMTLIGTQLIAVDISSGIHV--I 127

  Fly   146 STEDVYLEVPF---RSEEFQITAVTHPPTYINKIVLGSQQGQLKILNIKKNSVVCTLSH-HDSRI 206
            .|.:..|::..   .|::|:|||:.||.||:||||:||..|::||:|.:...|:..... .||||
 Worm   128 DTSEGGLQMSLLMEGSDDFEITAICHPSTYLNKIVVGSSTGRMKIINFRTGKVIHEFQRSFDSRI 192

  Fly   207 TCIEPSPALDVVAVGHGDGTIILLNLKFDEVLMSFQQDWGQVTNLSFRTDGPPILVSACSNGYMA 271
            |.||.:.|||||.||..:|.::|.|:|.|:::.||:.| .::||::||.||...:|:|..||.||
 Worm   193 TIIEQTTALDVVVVGLENGEVMLFNVKMDKIITSFRHD-AKITNVAFRDDGESTMVTADKNGTMA 256

  Fly   272 FWNLEERKLAGQLQA-HEESVTTAICLPSEPVVFTTSPDNSMRMFVFDMPDGGARQLRIREGHTK 335
            .|:||:::|.|::.. |.:.:.....:|.||::.:.|.|||:|:::||..||..|:|...|||:|
 Worm   257 VWDLEKQELIGKITGIHSDEINCLYFVPGEPIMLSASLDNSLRLWIFDSADGMPRELVRLEGHSK 321

  Fly   336 PPFCIRYHGSSGVSILSSGEDSTMRVFSTISESLNKSMGRATYNPKATKKKNRFEHDKFGMPPIL 400
            |...|::.|..  .:||:|:|.::|.:...|.::.:.:|......|..|:........||.
 Worm   322 PCASIKFVGKD--HVLSAGKDGSIRKYDVSSLTMRQKLGTVGQGVKLNKEVQNVAEMAFGW---- 380

  Fly   401 EFTSDTAREKEWDNIAAIHAGVIQTTTWSFGKNRMGEHRLVPKQFQNSNRTNF-QNETTCIVLTH 464
                  .||..|:|:........:.|||....|..|...|...:|:  .:.:| ....|.:.::.
 Worm   381 ------QREAAWNNVFCRQVNDTKITTWQTRNNTSGAFTLEHDRFK--KKVDFIDANATALCVSP 437

  Fly   465 CGNFVIIGYSSGDIERFNIQSGLHRATY----------------------------GSPAHKMAV 501
            |||||.||||:|.|::||.|||.|..::                            .:||....:
 Worm   438 CGNFVFIGYSTGHIDQFNAQSGRHVHSFTASTTVKKSKKSKNPRKGPTKTNGDIHNDTPAADSPI 502

  Fly   502 RGLASDNLNQTVISGCSEGLLKFWSFKGK--------------VDKPLATLRLADGIALIRQHRE 552
            ..|:.|...:.::|..::|.:.|||...|              :..|..:..|...:|:....:|
 Worm   503 TSLSVDQRGKELMSTDAQGHILFWSLSTKAINAKMFKKDVRLGICAPCPSNSLVALVAIAENGKE 567

  Fly   553 SSMLAIGLETFKIFVVDMHTRVIVRKF--VGHTAKLNDLTFSPDSRWLITAAMDSTIKVWDIPSS 615
            |           :.:||.....:.|.|  ||:  |:|.:|||.|.:||:.|..||.|:|:|:.:|
 Worm   568 S-----------VILVDTVCHRVARAFETVGN--KVNAMTFSSDGKWLLVADNDSYIRVFDVATS 619

  Fly   616 YMVDHFRVEAPCVSLSMSPNGDFLATAHVGLLGIYLWANKTLF-NQISLRSIDPLEPAPYVGLPT 679
            .::|......||:|:|.:..|.:|||.|.|...:|.||||.|| ..|::|:    .||.|  ||:
 Worm   620 QLIDVLLFSKPCISMSYNETGQYLATVHEGERAVYTWANKVLFVAHINIRA----HPADY--LPS 678

  Fly   680 NVCDAMELEDGMKELEIDEEDESKLGELVDTKYETPTQLSEELITLSGLAASRWQNLLDLELIKQ 744
            ....:.| |.|..:::.||:|.:.|.: .|.|.....|:.|.|:|.|||.:|||.||.||.|||:
 Worm   679 WSMISTE-EGGTCDIDDDEDDLTTLMD-QDIKAMKELQIDENLVTFSGLPSSRWANLPDLALIKE 741

  Fly   745 RNKPKAPPKAPKQAPFFL---PTVSGLELRFDVEN-GQKEEDESR--IRKASTLNNLTAFGQLLE 803
            ||||....|..|||||||   .|:.|.|  |:.|| |.:.:.:||  ..|.:.|...::|..||.
 Worm   742 RNKPTDAVKKIKQAPFFLSASATLDGFE--FETENIGDEMDGDSRYITSKRNLLELESSFTTLLR 804

  Fly   804 --ETADSLDFASAVAHLTQLGPSMVDFEIKSLHPEAGGTLLAMLQFLKLVKFMFGTNLNFELAQS 866
              :|.|.|  ..|...|..:..|.:||:|::|:|:.......||  |:::|    |..||||.|:
 Worm   805 NAKTRDHL--LDAFKTLQNMSLSAIDFQIRTLNPKTIPIFFRML--LEVLK----TKTNFELVQA 861

  Fly   867 YLSVFLRSH-------GLGLTEFPDLVKELRTVSQVQQEAWQRVEEKLIYGTGVVAALRN 919
            |.:...:.|       ..|.:|..:|.:.|..::|||.|:|..:|...:....||..::|
 Worm   862 YAATATKIHRTIMWNASEGASEHEELTEVLEEMAQVQMESWNEMENLFVENMAVVQWIKN 921

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9799	NP_650284.2	WD40 repeat	84..116	CDD:293791	5/31 (16%)
		WD40	111..372	CDD:475233	98/272 (36%)
		WD40 repeat	162..201	CDD:293791	18/38 (47%)
		WD40	198..642	CDD:441893	146/490 (30%)
		WD40 repeat	206..242	CDD:293791	17/35 (49%)
		WD40 repeat	249..285	CDD:293791	17/35 (49%)
		WD40 repeat	291..331	CDD:293791	14/39 (36%)
		WD40 repeat	337..364	CDD:293791	7/26 (27%)
		WD40 repeat	408..447	CDD:293791	11/38 (29%)
		WD40 repeat	458..496	CDD:293791	18/65 (28%)
		WD40 repeat	502..540	CDD:293791	9/51 (18%)
		WD40 repeat	545..580	CDD:293791	7/36 (19%)
		WD40 repeat	587..622	CDD:293791	15/34 (44%)
		Utp21	717..918	CDD:461219	78/215 (36%)
Y45F10D.7	NP_001369795.1	WD40 repeat	87..142	CDD:293791	12/64 (19%)
		WD40 repeat	148..185	CDD:293791	18/36 (50%)
		WD40	152..357	CDD:475233	82/207 (40%)
		WD40	161..618	CDD:441893	146/484 (30%)
		WD40 repeat	193..228	CDD:293791	16/34 (47%)
		WD40 repeat	233..271	CDD:293791	17/37 (46%)
		WD40 repeat	278..318	CDD:293791	14/39 (36%)
		WD40 repeat	323..358	CDD:293791	8/36 (22%)
		WD40 repeat	371..424	CDD:293791	13/64 (20%)
		WD40 repeat	430..466	CDD:293791	18/35 (51%)
		WD40 repeat	502..528	CDD:293791	6/25 (24%)
		WD40 repeat	546..584	CDD:293791	8/48 (17%)
		WD40 repeat	591..626	CDD:293791	15/34 (44%)
		Utp21	714..920	CDD:461219	78/215 (36%)