DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Droj2 and dnaja4.2

DIOPT Version :9

Sequence 1:	NP_650283.1	Gene:	Droj2 / 41646	FlyBaseID:	FBgn0038145	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001016990.1	Gene:	dnaja4.2 / 549744	XenbaseID:	XB-GENE-5891666	Length:	401	Species:	Xenopus tropicalis

Alignment Length:	394	Identity:	203/394 - (51%)
Similarity:	280/394 - (71%)	Gaps:	11/394 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVKETGYYDILGVKPNATPDELKKAYRKLALKYHPDKNPNEGEKFKAISQAYEVLSDADKRQVYD 65
            |||||.|||:|||:|:|:.:|:::|:|:|||||||||||:.|||||.||:|||:|.|:.||::||
Frog     1 MVKETEYYDLLGVRPSASSEEIRRAFRRLALKYHPDKNPSAGEKFKQISKAYEILHDSHKRELYD 65

  Fly    66 EGGEAAIKKGGADSG---DFRNPMDFFEKFFGAGFGGSGGGRRRERRGKDVVHQMSVQLEELYNG 127
            .|||.|:.  |..:|   .|.:|:|.|..|||   |.:....:.||:||.|.|.:.|.||:||||
Frog    66 RGGEDALT--GNSTGCRSAFDSPLDIFNLFFG---GSTRVHHQAERKGKSVAHHLPVSLEDLYNG 125

  Fly   128 ATRKLQLQKNVICDKCEGRGGKKGSIEKCLQCRGNGVETRVQQIAPGIMQHIEQVCRKCSGTGET 192
            |||||.||||.||.||:|.|.|:|||.||.:|:|.|:|..:....||:|..|:..|.:|:|.||.
Frog   126 ATRKLSLQKNAICAKCKGSGAKQGSITKCPKCQGCGIEVHLLTHIPGVMSQIQTPCSECNGKGEC 190

  Fly   193 IQEKDRCKNCSGRKTVRERKVLEVHIEKGMRDGQKIVFTGEGDHEPESQPGDIIILLDEKEHSTF 257
            |:.:|||:.|||||.:||:|:|.|||:|||:.||||:|..|||..|..|||||||:||:|.|..|
Frog   191 IRLRDRCQVCSGRKIIREKKILTVHIDKGMKSGQKIIFHEEGDQAPGLQPGDIIIVLDQKSHPVF 255

  Fly   258 AHAGQDLMMKMPLQLVEALCGFQRIVKTLDDRDLIVSTQPGEVIRHEMTKCIAEEGMPIFKNPME 322
            ...|.||:|||.:||.:||||.::.:||||.|.|:|::||||||:....|||.:|||||::|..|
Frog   256 QRKGHDLVMKMEIQLADALCGCRQSIKTLDGRTLLVTSQPGEVIKPGDIKCIPKEGMPIYRNLYE 320

  Fly   323 KGTLIIQFEVIFPEV--INPSVVPTLKQCLPPAPEVDIPIDAEQTVLEDFDP-KQRRQQHQRMAY 384
            ||:|||||::.|||.  :|...:..|:...|...|..|..|.|:..|.:::| :.::|:.::.||
Frog   321 KGSLIIQFQIHFPESGWLNGEHLTQLQGLFPSREEPIITEDMEEVSLAEYNPYEDQKQRGRQEAY 385

  Fly   385 DEDD 388
            :||:
Frog   386 EEDE 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Droj2	NP_650283.1	PTZ00037	2..398	CDD:240236	202/393 (51%)
		DnaJ	7..65	CDD:278647	36/57 (63%)
		DnaJ_C	112..336	CDD:199909	126/223 (57%)
		DnaJ_zf	140..206	CDD:199908	31/65 (48%)
dnaja4.2	NP_001016990.1	PTZ00037	2..398	CDD:240236	202/393 (51%)
		DnaJ	6..65	CDD:278647	36/58 (62%)
		DnaJ_C	113..335	CDD:199909	126/221 (57%)
		DnaJ_zf	138..204	CDD:199908	31/65 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1012379at2759
OrthoFinder	1	1.000	-	-		FOG0000718
OrthoInspector	1	1.000	-	-		otm48775
Panther	1	1.100	-	-	O	PTHR43888
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X359
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.110