DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Droj2 and DNAJB12

DIOPT Version :9

Sequence 1:	NP_650283.1	Gene:	Droj2 / 41646	FlyBaseID:	FBgn0038145	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001352009.1	Gene:	DNAJB12 / 54788	HGNCID:	14891	Length:	377	Species:	Homo sapiens

Alignment Length:	153	Identity:	62/153 - (40%)
Similarity:	78/153 - (50%)	Gaps:	31/153 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 YYDILGVKPNATPDELKKAYRKLALKYHPDKN--PNEGEKFKAISQAYEVLSDADKRQVYDEGGE 69
            ||:||||...|:.::||||||:||||:|||||  |...|.||||..||.|||:.:||:.||:.|:
Human   111 YYEILGVSRGASDEDLKKAYRRLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQFGD 175

  Fly    70 --AAIKKGGADSGDFR-------NPMDFFEKFFGAGFGGSGGGRRRERRGKDVVHQMSVQLEELY 125
              :...:.|...|||.       :|.|.|..|||.||..|.            ||..|
Human   176 DKSQAARHGHGHGDFHRGFEADISPEDLFNMFFGGGFPSSN------------VHVYS------- 221

  Fly   126 NGATRKLQLQKNVICDKCEGRGG 148
            ||..|....|:....|. :|.||
Human   222 NGRMRYTYQQRQDRRDN-QGDGG 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Droj2	NP_650283.1	PTZ00037	2..398	CDD:240236	62/153 (41%)
		DnaJ	7..65	CDD:278647	35/59 (59%)
		DnaJ_C	112..336	CDD:199909	11/37 (30%)
		DnaJ_zf	140..206	CDD:199908	4/9 (44%)
DNAJB12	NP_001352009.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	45..92
		DnaJ	110..>236	CDD:333066	58/143 (41%)
		DUF1977	268..368	CDD:312722
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910