DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Droj2 and dnaja1

DIOPT Version :9

Sequence 1:	NP_650283.1	Gene:	Droj2 / 41646	FlyBaseID:	FBgn0038145	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001011012.1	Gene:	dnaja1 / 496421	XenbaseID:	XB-GENE-976936	Length:	400	Species:	Xenopus tropicalis

Alignment Length:	408	Identity:	245/408 - (60%)
Similarity:	310/408 - (75%)	Gaps:	13/408 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVKETGYYDILGVKPNATPDELKKAYRKLALKYHPDKNPNEGEKFKAISQAYEVLSDADKRQVYD 65
            ||.||.||||||||||:|||||||||||||||||||||||||||||.||||||||||:.||.:||
Frog     1 MVVETAYYDILGVKPNSTPDELKKAYRKLALKYHPDKNPNEGEKFKQISQAYEVLSDSKKRDLYD 65

  Fly    66 EGGEAAIKKGGADSGDFRNPMDFFEKFFGAGFGGSGGGR-RRERRGKDVVHQMSVQLEELYNGAT 129
            :|||.|||:||...|.|.:|||.|:.|||      |||| :||||||:||||:||.||:||||||
Frog    66 KGGEQAIKEGGMGGGGFASPMDIFDMFFG------GGGRMQRERRGKNVVHQLSVSLEDLYNGAT 124

  Fly   130 RKLQLQKNVICDKCEGRGGKKGSIEKCLQCRGNGVETRVQQIAPGIMQHIEQVCRKCSGTGETIQ 194
            |||.:|||.|||||||||||||::|.|..|||.|::.|:.|:.||::|.|:.||.:|.|.||.|.
Frog   125 RKLAVQKNTICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQLGPGMVQQIQSVCPECQGQGERIN 189

  Fly   195 EKDRCKNCSGRKTVRERKVLEVHIEKGMRDGQKIVFTGEGDHEPESQPGDIIILLDEKEHSTFAH 259
            .|||||:|:|||.|||:|:|||||:|||:|||||.|:||||.||..:.|||||:||:|:||.|..
Frog   190 PKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFSGEGDQEPGLEAGDIIIVLDQKDHSVFTR 254

  Fly   260 AGQDLMMKMPLQLVEALCGFQRIVKTLDDRDLIVSTQPGEVIRHEMTKCIAEEGMPIFKNPMEKG 324
            ..:||::.|.::|||||||||:.:.|||.|.:|:::.||::::|...||:..|||||::.|.:||
Frog   255 RNEDLIIHMEIELVEALCGFQKPIVTLDSRTIIITSHPGQIVKHGDVKCVLNEGMPIYRRPYDKG 319

  Fly   325 TLIIQFEVIFP--EVINPSVVPTLKQCLPPAPEVDIPIDAEQTVLEDFDPKQRRQQH-QRMAYDE 386
            .||:||:|.||  ..|:|..:|.|::.||...|::...|.||..|.||||.|:|::| ...||.:
Frog   320 RLIVQFQVNFPASNSISPDKLPLLEKLLPARKEIEETEDMEQAELMDFDPSQQRRRHFNGEAYHD 384

  Fly   387 DDGGYQDGPRV-QQCTSS 403
            ||.  .|.||. .||.:|
Frog   385 DDD--DDHPRSGVQCQTS 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Droj2	NP_650283.1	PTZ00037	2..398	CDD:240236	241/400 (60%)
		DnaJ	7..65	CDD:278647	51/57 (89%)
		DnaJ_C	112..336	CDD:199909	133/225 (59%)
		DnaJ_zf	140..206	CDD:199908	38/65 (58%)
dnaja1	NP_001011012.1	PTZ00037	7..397	CDD:240236	238/397 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	304	1.000	Domainoid score	I1374
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	504	1.000	Inparanoid score	I1311
OMA	1	1.010	-	-		QHG53515
OrthoDB	1	1.010	-	-		D1012379at2759
OrthoFinder	1	1.000	-	-		FOG0000718
OrthoInspector	1	1.000	-	-		otm48775
Panther	1	1.100	-	-	O	PTHR43888
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R684
SonicParanoid	1	1.000	-	-		X359
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.110