DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Droj2 and dnajb1a

DIOPT Version :9

Sequence 1:	NP_650283.1	Gene:	Droj2 / 41646	FlyBaseID:	FBgn0038145	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001003571.1	Gene:	dnajb1a / 445177	ZFINID:	ZDB-GENE-040801-90	Length:	335	Species:	Danio rerio

Alignment Length:	395	Identity:	127/395 - (32%)
Similarity:	188/395 - (47%)	Gaps:	113/395 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 YYDILGVKPNATPDELKKAYRKLALKYHPDKNPNEG--EKFKAISQAYEVLSDADKRQVYDEGGE 69
            ||.|||::..|:.:|:||||||.||::|||||.:.|  :|||.|::||:|||||.|:.:||..||
Zfish     5 YYRILGIEKGASDEEIKKAYRKQALRFHPDKNKSAGAEDKFKEIAEAYDVLSDAKKKDIYDRYGE 69

  Fly    70 AAIKKGGADSG-----------------DF---RNPMDFF-------------EKFFGA-GFGGS 100
            ..: ||.|.||                 :|   |:|.|.|             :..||| |.||.
Zfish    70 DGL-KGHAGSGTNGPSYTFHGDPHAMFAEFFGGRSPFDHFFASAGGPNDGMDIDDPFGAFGMGGM 133

  Fly   101 GG-------------GRRRERRGKDVVHQMSVQLEELYNGATRKLQLQKNVICDKCEGRGGKKGS 152
            ||             |.|.:::...|||::.|.|||::.|.|:|:::.:
Zfish   134 GGFPRSFKSRVGGPHGSREKKKDPPVVHELKVSLEEVFAGCTKKMKISR---------------- 182

  Fly   153 IEKCLQCRGNGVETRVQQIAPGIMQHIEQVCRKCSGTGETIQEKDRCKNCSGRKTVRERKVLEVH 217
                            :::.|                          ..||.|   .|.|:|.|.
Zfish   183 ----------------KRLNP--------------------------DGCSMR---NEDKILTVD 202

  Fly   218 IEKGMRDGQKIVFTGEGDHEPESQPGDIIILLDEKEHSTFAHAGQDLMMKMPLQLVEALCGFQRI 282
            |::|.::|.||.|..|||..|.:.|.||:.::.:|.||.|...|.|::....:.|.|||||....
Zfish   203 IKRGWKEGTKITFPKEGDETPTNIPADIVFVVKDKIHSVFRRDGSDIIYPARISLREALCGCTIN 267

  Fly   283 VKTLDDRDLIVSTQPGEVIRHEMTKCIAEEGMPIFKNPMEKGTLIIQFEVIFPEVINPSVVPTLK 347
            ..|||.|.:.||::  :||:..|.|.|..||:|:.|.|.::|.::::|.|.||:.:.|.....|.
Zfish   268 APTLDGRTVTVSSR--DVIKPGMKKRIVGEGLPLSKCPEKRGDMVLEFSVKFPDKLGPGAREALV 330

  Fly   348 QCLPP 352
            |.|||
Zfish   331 QILPP 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Droj2	NP_650283.1	PTZ00037	2..398	CDD:240236	127/395 (32%)
		DnaJ	7..65	CDD:278647	33/59 (56%)
		DnaJ_C	112..336	CDD:199909	63/223 (28%)
		DnaJ_zf	140..206	CDD:199908	3/65 (5%)
dnajb1a	NP_001003571.1	DnaJ	1..335	CDD:223560	125/393 (32%)
		DnaJ	4..65	CDD:278647	33/59 (56%)
		DnaJ_C	157..321	CDD:199909	64/226 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53515
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920