DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Droj2 and Dnajc11

DIOPT Version :9

Sequence 1:	NP_650283.1	Gene:	Droj2 / 41646	FlyBaseID:	FBgn0038145	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001102164.1	Gene:	Dnajc11 / 362666	RGDID:	1307731	Length:	559	Species:	Rattus norvegicus

Alignment Length:	381	Identity:	88/381 - (23%)
Similarity:	139/381 - (36%)	Gaps:	121/381 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 YYDILGVKPNATPDELKKAYRKLALKYHPDKN-----PNEGEK-FKAISQAYEVLSDADKRQVYD 65
            ||.:|.|:..|:.:|||.|||:|.:.|||||:     .::.|: |..:.||||||||...|.:||
  Rat    15 YYSLLNVRREASAEELKAAYRRLCMLYHPDKHRDPELKSQAERLFNLVHQAYEVLSDPQTRAIYD 79

  Fly    66 ---------EGGEAAIKKGGADSGDFRNPMDFFEKFFGAGFGGSGGGRRRERRGKDVVHQMSVQL 121
                     ||.|...:|        |.|.:..|:|           .|.:|..::
  Rat    80 IYGKRGLEMEGWEVVERK--------RTPAEIREEF-----------ERLQREREE--------- 116

  Fly   122 EELYNGATRKLQLQKNVICDKCEGRGGKKGSIEKCLQCRGNGVETRVQQIAPGIMQHIEQVCRKC 186
                    ||||.:.|           .||:|..       ||:      |..:....::.....
  Rat   117 --------RKLQQRTN-----------PKGTISV-------GVD------ATDLFDRYDEEYEDV 149

  Fly   187 SGTG---ETIQEKDRCKNCSGRKTVRERKVL--EVHIEKGMRDGQ-----KIVFTGEGDHEPESQ 241
            ||:|   ..|.:....::.....|..:..:|  .:..:.|...|.     :.|.:.:|..|.|..
  Rat   150 SGSGFPQIEINKMHISQSIEAPLTATDTAILSGSLSTQNGNGGGSINFALRRVTSAKGWGELEFG 214

  Fly   242 PGDIIILLDEKEHSTFAHAGQDLMMKM-PLQLVEALCGFQRIVKTLDDRDLIVSTQPGEVIRHEM 305
            .||:       :...|   |..|...: |...|...|..|     ...|.:    :||      :
  Rat   215 AGDL-------QGPLF---GLKLFRNLTPRCFVTTNCALQ-----FSSRGI----RPG------L 254

  Fly   306 TKCIAEEGMPIFKNPMEKGTL-IIQFEVIFPEVINPSVVPTLKQC-LPPAPEVDIP 359
            |..:|..        ::|.|: .:|:.......:|.|:|...|.| ...|.::.||
  Rat   255 TTVLARN--------LDKNTVGYLQWRWGIQSAMNTSIVRDTKTCHFTVALQLGIP 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Droj2	NP_650283.1	PTZ00037	2..398	CDD:240236	88/381 (23%)
		DnaJ	7..65	CDD:278647	28/63 (44%)
		DnaJ_C	112..336	CDD:199909	40/235 (17%)
		DnaJ_zf	140..206	CDD:199908	10/68 (15%)
Dnajc11	NP_001102164.1	DnaJ	14..79	CDD:278647	28/63 (44%)
		Selenoprotein_S	372..>447	CDD:284376
		DUF3395	417..549	CDD:288708
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910