DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Droj2 and DnaJ-H

DIOPT Version :9

Sequence 1:	NP_650283.1	Gene:	Droj2 / 41646	FlyBaseID:	FBgn0038145	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001260431.1	Gene:	DnaJ-H / 34707	FlyBaseID:	FBgn0032474	Length:	440	Species:	Drosophila melanogaster

Alignment Length:	401	Identity:	138/401 - (34%)
Similarity:	215/401 - (53%)	Gaps:	23/401 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 YDILGVKPNATPDELKKAYRKLALKYHPDKNPNEGEKFKAISQAYEVLSDADKRQVYDEGGEAAI 72
            ||:|.|.|:||.:|:||.|||||.::||||||:.|:|||.||.|||||||.:||::||..|...:
  Fly     7 YDVLKVAPDATDEEIKKNYRKLAKEFHPDKNPDAGDKFKEISFAYEVLSDPEKRRIYDRYGLKGL 71

  Fly    73 KKGGADSGDFRNPMDFFEKFFGAGFGGSGGGRRRERRGKDVVHQMSVQLEELY-NGATRKLQLQK 136
            ::|   :..|.:..:||.::|......|.|   |.||...||.::.:.|||:| .|..:|::..:
  Fly    72 QEG---AEGFSDASEFFAQWFPFDRVSSEG---RGRRNGKVVVKVELTLEEIYVGGMKKKVEYNR 130

  Fly   137 NVICDKCEGRGGKKGSIEKCLQCRGNGVETRVQQIAPGIMQHIEQVCRKCSGTGETIQEKDRCKN 201
            ..:|.||.|.||.|.:.|.|..|.|.|   |........:...:..|..|.|.|.||::..:|..
  Fly   131 QKLCSKCNGDGGPKEAHESCETCGGAG---RAAAFTFMGLSPFDTTCPTCDGRGFTIRDDKKCSP 192

  Fly   202 CSGRKTVRERKVLEVHIEKGMRDGQKIVFTGEGDHEPESQPGDIIILLDEKEHSTFAHAGQDLMM 266
            |.|...|.::...::.:|:|.....|:.|..||......:.||:|:::.:.||..|.....:|.|
  Fly   193 CQGSGFVEQKMKRDLVVERGAPHMLKVPFANEGHQMRGGEFGDLIVVISQMEHPIFQRRHANLYM 257

  Fly   267 K-MPLQLVEALCGFQRIVKTLDDRDLIVSTQPGEVIRHEMTKCIAEEGMPIFKNPMEKGTLIIQF 330
            : :.:.:.|||||:....|.||.|::.:.|.||||::|...|.:...|||:|....:.|.|.::|
  Fly   258 RDLEINITEALCGYSHCFKHLDGRNVCLRTYPGEVLQHNQIKMVRGSGMPVFNKATDSGDLYMKF 322

  Fly   331 EVIFPE---VINPSVVPTLKQCLPPAPEVDIPIDAEQTVLEDFDPKQRRQQHQRMAYDEDDGGYQ 392
            :|.||:   ...|.:. .|:..|||...:.||.:||:..:.|:.|:.|:|        ||:.|..
  Fly   323 KVKFPDNDFATAPQLA-MLEDLLPPRQPIVIPKNAEEVQMTDYKPQPRQQ--------EDEDGQS 378

  Fly   393 DGPRVQQCTSS 403
            ......||.::
  Fly   379 SHFEGVQCQTA 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Droj2	NP_650283.1	PTZ00037	2..398	CDD:240236	136/394 (35%)
		DnaJ	7..65	CDD:278647	36/56 (64%)
		DnaJ_C	112..336	CDD:199909	70/225 (31%)
		DnaJ_zf	140..206	CDD:199908	22/65 (34%)
DnaJ-H	NP_001260431.1	DnaJ	1..363	CDD:223560	129/365 (35%)
		DnaJ	5..64	CDD:278647	36/56 (64%)
		DnaJ_C	106..329	CDD:199909	71/225 (32%)
		DnaJ_zf	134..197	CDD:199908	22/65 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440489
Domainoid	1	1.000	82	1.000	Domainoid score	I2910
eggNOG	1	0.900	-	-		E2759_KOG0712
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S577
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1012379at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43888
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.800