DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Droj2 and Dnaja4

DIOPT Version :9

Sequence 1:	NP_650283.1	Gene:	Droj2 / 41646	FlyBaseID:	FBgn0038145	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001020582.1	Gene:	Dnaja4 / 300721	RGDID:	1310035	Length:	555	Species:	Rattus norvegicus

Alignment Length:	407	Identity:	246/407 - (60%)
Similarity:	314/407 - (77%)	Gaps:	14/407 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVKETGYYDILGVKPNATPDELKKAYRKLALKYHPDKNPNEGEKFKAISQAYEVLSDADKRQVYD 65
            |||||.|||||||||:|:|:|:|||||||||||||||||:||||||.||||||||||..||.:||
  Rat   159 MVKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGEKFKLISQAYEVLSDPKKRDIYD 223

  Fly    66 EGGEAAIKKGGADSGDFRNPMDFFEKFFGAGFGGSGGGR-RRERRGKDVVHQMSVQLEELYNGAT 129
            :|||.|||:||:.|..|.:|||.|:.|||      |||| .||||||:||||:||.||:||||.|
  Rat   224 QGGEQAIKEGGSGSPSFSSPMDIFDMFFG------GGGRMTRERRGKNVVHQLSVTLEDLYNGIT 282

  Fly   130 RKLQLQKNVICDKCEGRGGKKGSIEKCLQCRGNGVETRVQQIAPGIMQHIEQVCRKCSGTGETIQ 194
            :||.||||:||:||||.||||||:|||..|:|.|::..:|||.||::|.|:.||.:|.|.||.|.
  Rat   283 KKLALQKNIICEKCEGIGGKKGSVEKCPLCKGRGMQIHIQQIGPGMVQQIQTVCIECKGQGERIN 347

  Fly   195 EKDRCKNCSGRKTVRERKVLEVHIEKGMRDGQKIVFTGEGDHEPESQPGDIIILLDEKEHSTFAH 259
            .||||::|||.|..||:|::|||::|||:|||||:|.||||.|||.:|||:||:||:|:||.|..
  Rat   348 PKDRCEDCSGAKVTREKKIIEVHVDKGMKDGQKILFHGEGDQEPELEPGDVIIVLDQKDHSVFQR 412

  Fly   260 AGQDLMMKMPLQLVEALCGFQRIVKTLDDRDLIVSTQPGEVIRHEMTKCIAEEGMPIFKNPMEKG 324
            .|.||:|||.:||.||||||::.:||||||.||:|::.||||:|...||:..|||||:|.|:|||
  Rat   413 RGHDLIMKMKIQLSEALCGFKKTIKTLDDRVLIISSKSGEVIKHGDLKCVRNEGMPIYKAPLEKG 477

  Fly   325 TLIIQFEVIFPEV--INPSVVPTLKQCLPPAPEVDIPIDAEQTVLEDFDPKQRRQQHQRMAYDED 387
            .|||||.|:|||.  ::...:|.|:..|||..:|.|..|.:|..|::|:|.::..:..|.||:||
  Rat   478 MLIIQFLVVFPEKQWLSLEKLPQLEALLPPRQKVRITDDMDQVELKEFNPNEQSWRQHREAYEED 542

  Fly   388 DGGYQDGPRV-QQCTSS 403
            |    ||||. .||.::
  Rat   543 D----DGPRAGVQCQTA 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Droj2	NP_650283.1	PTZ00037	2..398	CDD:240236	243/399 (61%)
		DnaJ	7..65	CDD:278647	47/57 (82%)
		DnaJ_C	112..336	CDD:199909	139/223 (62%)
		DnaJ_zf	140..206	CDD:199908	38/65 (58%)
Dnaja4	NP_001020582.1	PTZ00037	144..552	CDD:240236	244/402 (61%)
		DnaJ	165..223	CDD:278647	47/57 (82%)
		DnaJ_C	264..490	CDD:199909	141/225 (63%)
		DnaJ_zf	293..359	CDD:199908	38/65 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	312	1.000	Domainoid score	I1264
eggNOG	1	0.900	-	-		E2759_KOG0712
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23110
Inparanoid	1	1.050	507	1.000	Inparanoid score	I1280
OMA	1	1.010	-	-		QHG53515
OrthoDB	1	1.010	-	-		D1012379at2759
OrthoFinder	1	1.000	-	-		FOG0000718
OrthoInspector	1	1.000	-	-		otm45687
orthoMCL	1	0.900	-	-		OOG6_100614
Panther	1	1.100	-	-	LDO	PTHR43888
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X359
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840