DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Droj2 and DNAJB5

DIOPT Version :9

Sequence 1:	NP_650283.1	Gene:	Droj2 / 41646	FlyBaseID:	FBgn0038145	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001128477.1	Gene:	DNAJB5 / 25822	HGNCID:	14887	Length:	420	Species:	Homo sapiens

Alignment Length:	419	Identity:	131/419 - (31%)
Similarity:	189/419 - (45%)	Gaps:	133/419 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KETG----------YYDILGVKPNATPDELKKAYRKLALKYHPDKN--PNEGEKFKAISQAYEVL 55
            |||.          ||.|||:...|..||:||||||:|||||||||  ||..||||.|::||:||
Human    63 KETSAGPVAVMGKDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNAEEKFKEIAEAYDVL 127

  Fly    56 SDADKRQVYDEGGEAAIKKG----GADSGDFR------------------NPMDFF--------- 89
            ||..||.:||:.||..:|.|    |..||.|.                  ||.|.|
Human   128 SDPKKRGLYDQYGEEGLKTGGGTSGGSSGSFHYTFHGDPHATFASFFGGSNPFDIFFASSRSTRP 192

  Fly    90 --------------EKFFGA----GFGGSGGGRRR-------ERRGKD--VVHQMSVQLEELYNG 127
                          |..|||    ||.|...|.||       .|:.:|  |||::.|.|||:|:|
Human   193 FSGFDPDDMDVDEDEDPFGAFGRFGFNGLSRGPRRAPEPLYPRRKVQDPPVVHELRVSLEEIYHG 257

  Fly   128 ATRKLQLQKNVICDKCEGRGGKKGSIEKCLQCRGNGVETRVQQIAPGIMQHIEQVCRKCSGTGET 192
            :|:::::.:                                               |:.:..|.|
Human   258 STKRMKITR-----------------------------------------------RRLNPDGRT 275

  Fly   193 IQEKDRCKNCSGRKTVRERKVLEVHIEKGMRDGQKIVFTGEGDHEPESQPGDIIILLDEKEHSTF 257
            ::.:|              |:|.:.|::|.::|.||.|..|||..|::.|.||:.:|.:|.|:.|
Human   276 VRTED--------------KILHIVIKRGWKEGTKITFPKEGDATPDNIPADIVFVLKDKPHAHF 326

  Fly   258 AHAGQDLMMKMPLQLVEALCGFQRIVKTLDDRDLIVSTQPGEVIRHEMTKCIAEEGMPIFKNPME 322
            ...|.:::....:.|.|||||....:.|:|.|  ::.....:||:....|.:..||:|..|.|.:
Human   327 RRDGTNVLYSALISLKEALCGCTVNIPTIDGR--VIPLPCNDVIKPGTVKRLRGEGLPFPKVPTQ 389

  Fly   323 KGTLIIQFEVIFPEVINPSVVPTLKQCLP 351
            :|.||::|:|.||:.:.|.....|||.||
Human   390 RGDLIVEFKVRFPDRLTPQTRQILKQHLP 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Droj2	NP_650283.1	PTZ00037	2..398	CDD:240236	131/419 (31%)
		DnaJ	7..65	CDD:278647	38/59 (64%)
		DnaJ_C	112..336	CDD:199909	58/225 (26%)
		DnaJ_zf	140..206	CDD:199908	4/65 (6%)
DNAJB5	NP_001128477.1	DnaJ	72..415	CDD:223560	124/405 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53515
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920