DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Droj2 and SPBC405.06

DIOPT Version :9

Sequence 1:	NP_650283.1	Gene:	Droj2 / 41646	FlyBaseID:	FBgn0038145	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_596309.1	Gene:	SPBC405.06 / 2540773	PomBaseID:	SPBC405.06	Length:	413	Species:	Schizosaccharomyces pombe

Alignment Length:	422	Identity:	140/422 - (33%)
Similarity:	221/422 - (52%)	Gaps:	34/422 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVKETGYYDILGVKPNATPDELKKAYRKLALKYHPDKNP-----NEGEKFKAISQAYEVLSDADK 60
            ||.:|..||||.|...|:.:|:||:|::|||.:||||.|     ...|:|:.:.:||::|.|.:.
pombe     1 MVVDTKLYDILEVHFEASAEEIKKSYKRLALLHHPDKAPIHEKEEAAERFRGVQEAYDILKDPES 65

  Fly    61 RQVYDEGGEAAIKKGGADSGDFRNPMDFFEKFFGAGFGGSGGG----RRRERRGKDVVHQMSVQL 121
            |::||..|..:......|.|  .|..|...:.||..|...|.|    |.|:|||.||:|...:.|
pombe    66 REMYDMYGMNSDSNSQFDGG--VNLDDVLAQMFGMNFEAGGPGKNVPRDRKRRGSDVIHDYEISL 128

  Fly   122 EELYNGATRKLQLQKNVICDKCEGRGGKKGSIEK-CLQCRGNGVETRVQQIAPGIMQHIEQVCRK 185
            |:::.|...||:..:|.:|.:|:|||||:.:.|| ||.|.|.||:..::.:.|..:.:.:.:|..
pombe   129 EDMFKGKEVKLRATRNTLCPRCQGRGGKRFAKEKPCLSCDGKGVKQHLKHVGPHHVTNSQVICDT 193

  Fly   186 CSGTGETIQEKDRCKNCSGRKTVRERKVLEVHIEKGMRDGQKIVFTGEGDHEPESQPGDIIILLD 250
            |:|.|.:.:.|||||:|.|..||.|:::|...:.:..::..||:..|..|......|||:|:.|.
pombe   194 CNGKGVSFRGKDRCKHCKGSGTVPEQRMLSFFVNRSAKENDKIIQRGMADEAYGITPGDVILQLH 258

  Fly   251 EKEHSTFAHAGQDLMMKMPLQLVEALCGFQRIV-KTLDDRDLIVSTQPGEVIRHEMTKCIAEEGM 314
            :|.|..|...|.||..|:.:.|.|||.||.|:: .|||.|.|......|:::.......|..|||
pombe   259 QKPHPVFERLGDDLKAKLKISLAEALTGFNRVILTTLDGRGLEYVQPIGKILHPGDCLIIPGEGM 323

  Fly   315 PIFKNPME--KGTLIIQFEVIFPE--VINPSVVPTLKQCLPPAPEV----DIPIDAEQTV---LE 368
              :|:...  :|.|.::.::.||:  :|..:.:..|:..||..|:|    |..||:.:.|   :.
pombe   324 --YKDSKTDLRGDLYLEVDIEFPKDGLIGTTEIEILRDILPSIPKVSVMDDTLIDSVRGVPGDIS 386

  Fly   369 DFDPKQRRQQHQRMAYDEDDGGYQDGPRVQQC 400
            .|....|        |..:|.|.:....|.:|
pombe   387 HFGGDAR--------YANEDYGDETYEGVPEC 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Droj2	NP_650283.1	PTZ00037	2..398	CDD:240236	137/417 (33%)
		DnaJ	7..65	CDD:278647	25/62 (40%)
		DnaJ_C	112..336	CDD:199909	77/227 (34%)
		DnaJ_zf	140..206	CDD:199908	27/66 (41%)
SPBC405.06	NP_596309.1	DnaJ	5..379	CDD:223560	130/377 (34%)
		DnaJ	7..70	CDD:278647	25/62 (40%)
		DnaJ_C	118..346	CDD:199909	78/229 (34%)
		DnaJ_CXXCXGXG	147..214	CDD:279074	27/66 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0712
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770