Protein Alignment Droj2 and DNAJC8

DIOPT Version :9

• Sequence 1: NP_650283.1
• Gene: Droj2 / 41646
• FlyBaseID: FBgn0038145
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_055095.2
• Gene: DNAJC8 / 22826
• HGNCID: 15470
• Length: 253
• Species: Homo sapiens
• Alignment Length: 192
• Identity: 45/192 - (23%)
• Similarity: 82/192 - (42%)
• Gaps: 58/192 - (30%)

  Fly     8 YDILGVKPNATPDELKKAYRKLALKYHPDKNPNEGEK----FKAISQAYEVLSDAD--------- 59
            :::|.:.|..|.:|:||.:|:|::..|||||.::.::    |:|:.:||::|.|.:
Human    59 FEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVI 123

  Fly    60 --------------KRQVYDEGGEAAIKKGGAD---SGDFRNPMDFFEKFFGAGFGGSGGGRRRE 107
                          |:|:..||....:::...:   ...::..|..|.:.         ..:|:|
Human   124 QAGKEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAEL---------EIKRKE 179

  Fly   108 RRGKDVVHQMSVQLE---ELYNGATRKLQLQKNVICDKCEGRGGK-----------KGSIEK 155
            |..|: :|:...|.|   |....|.|:.:.|||..    |.|.|:           ||..||
Human   180 REAKE-MHERKRQREEEIEAQEKAKREREWQKNFE----ESRDGRVDSWRNFQANTKGKKEK 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Droj2	NP_650283.1	PTZ00037	2..398	CDD:240236	45/192 (23%)
		DnaJ	7..65	CDD:278647	21/83 (25%)
		DnaJ_C	112..336	CDD:199909	16/58 (28%)
		DnaJ_zf	140..206	CDD:199908	7/27 (26%)
DNAJC8	NP_055095.2	CbpA	51..>238	CDD:225124	45/192 (23%)
		DnaJ	57..112	CDD:99751	18/52 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	181..253		17/61 (28%)
		Nuclear localization signal. /evidence=ECO:0000305|PubMed:27133716	189..192		0/2 (0%)
		Nuclear localization signal. /evidence=ECO:0000305|PubMed:27133716	203..206		1/2 (50%)
		Essential for polyglutamine aggregation suppression. /evidence=ECO:0000269|PubMed:27133716	232..253		3/5 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910