DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8870 and f10

DIOPT Version :9

Sequence 1:	NP_731802.1	Gene:	CG8870 / 41645	FlyBaseID:	FBgn0038144	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_001015728.1	Gene:	f10 / 548445	XenbaseID:	XB-GENE-971433	Length:	464	Species:	Xenopus tropicalis

Alignment Length:	385	Identity:	95/385 - (24%)
Similarity:	161/385 - (41%)	Gaps:	84/385 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 GLIGSFLLMLQIILVPYSNGAGCQFDTECVNLDK---CPRTRA-VMNSSRKNIIGLRR--CGTNK 62
            |..|.....:::.|...:||   :.|..|..:|:   |..|.. ::..:.|:.:...:  ||...
Frog   114 GFEGKNCETVKLQLCSLNNG---ECDQYCKAVDRDVVCSCTNGYILGENGKSCLPTEKYSCGRRH 175

  Fly    63 VCCPKWETYLPHD------TCGQSRRKPTK-GKIPALN-------------------------EF 95
            :...:.||.| |:      |..|:..|..: |.:|..|                         |.
Frog   176 MKRERRETKL-HENDKKNHTDSQNEVKMNQTGTLPERNVTGINILNPNDPNVRIVGGRECSQGEC 239

  Fly    96 PWMAMLLYGNKNNLSQKLVPKCGGSLINNWYVLTAAHCVEYPFMDYPYALKTVRLGEHNTSTNPD 160
            ||.|:|:.......       |||::::..::||||||     |:.....|.| :||.||..:..
Frog   240 PWQALLVSDEDEGF-------CGGTILSREFILTAAHC-----MNQTKYFKVV-VGELNTKISEG 291

  Fly   161 RAIVNGRRQYAPLYMEIEVDQIITHEQFNRGRRLINDIALVRLKFPVRYTRAIQPICLPR---AQ 222
            ...::            :|::||.|.:|.:. ....|||:::||..:.:|..|.|.|:|.   |.
Frog   292 TESIH------------KVEKIIMHPRFVKS-TYDYDIAVIKLKEAINFTENIIPACIPDPEFAD 343

  Fly   223 KLAAHKRKFQASGW---PDMGQGIASEVLLRSFIAERHPDVCKSNYDFNLGSQICAGGLDG--ND 282
            ::..::.....||:   .:.|:..::..:|:....:||.  ||.:..|.:...:...|.|.  .|
Frog   344 QVLMNEPDAMVSGFGRIHERGRQASTLQMLQVPYIKRHS--CKESSTFAITENMFCAGFDTEVKD 406

  Fly   283 TSPGDSGGPLMETVIRGKVTLTYAAGIISYGQKPCVLKTCKPAFYTKTSYFFEWIKSKLQ 342
            ...||||||.: |..:|...:|   ||:|:|: .|..|. |...|||.|....|:|..|:
Frog   407 ACQGDSGGPHV-TPFKGTYFVT---GIVSWGE-GCARKG-KFGVYTKVSKLHRWLKGVLK 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8870	NP_731802.1	Tryp_SPc	93..340	CDD:238113	72/279 (26%)
CG8870	NP_731802.1	Tryp_SPc	93..337	CDD:214473	70/276 (25%)
f10	NP_001015728.1	GLA	22..84	CDD:214503
		EGF_CA	85..121	CDD:238011	2/6 (33%)
		FXa_inhibition	128..163	CDD:373209	8/37 (22%)
		Tryp_SPc	228..456	CDD:238113	70/261 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010