DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8870 and f10

DIOPT Version :9

Sequence 1:	NP_731802.1	Gene:	CG8870 / 41645	FlyBaseID:	FBgn0038144	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_958870.3	Gene:	f10 / 282670	ZFINID:	ZDB-GENE-021206-9	Length:	504	Species:	Danio rerio

Alignment Length:	252	Identity:	72/252 - (28%)
Similarity:	128/252 - (50%)	Gaps:	38/252 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 PWMAMLLYGNKNNLSQKLVPKCGGSLINNWYVLTAAHCVEYPFMDYPYALKTVRLGEHNTSTNPD 160
            ||.|:|:  |:||:.     .|||:::...::|:||||     |:...:::.| :||::|.....
Zfish   257 PWQALLI--NENNMG-----FCGGTILTEHFILSAAHC-----MNESLSIRVV-VGEYDTLVPEG 308

  Fly   161 RAIVNGRRQYAPLYMEIEVDQIITHEQFNRGRRLINDIALVRLKFPVRYTRAIQPICLPR---AQ 222
            |...:            :||:|:.|:.: :.....|||||::|..|:::|:.|.|.|||.   |:
Zfish   309 REATH------------DVDEILIHKNY-QPDTYHNDIALIKLSKPIKFTKYIIPACLPEMKFAE 360

  Fly   223 KLAAHKRKFQASGWPDMGQ-GIASEVLLRSFIAERHPDVCKSNYDFNL-GSQICAG-GLDGNDTS 284
            ::...:.....||:..:.: |::|.:|.:..:...:...|..:.:|.: |...||| ..:..|..
Zfish   361 RVLMQQDDGLVSGFGRVREGGLSSTILQKLTVPYVNRAKCIESSNFKISGRMFCAGYDQEEKDAC 425

  Fly   285 PGDSGGPLMETVIRGKVTLTYAAGIISYGQKPCVLKTCKPAFYTKTSYFFEWIKSKL 341
            .||||||   .|.|.|.| .:..|::|:|: .|..|. |...||:.|.:..||.:.:
Zfish   426 QGDSGGP---HVTRFKNT-WFITGVVSWGE-GCARKG-KYGVYTQVSKYIMWINNAM 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8870	NP_731802.1	Tryp_SPc	93..340	CDD:238113	72/249 (29%)
CG8870	NP_731802.1	Tryp_SPc	93..337	CDD:214473	70/246 (28%)
f10	NP_958870.3	GLA	19..82	CDD:214503
		EGF_CA	83..119	CDD:238011
		FXa_inhibition	126..161	CDD:291342
		Tryp_SPc	244..472	CDD:214473	70/246 (28%)
		Tryp_SPc	245..474	CDD:238113	72/248 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010