DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8870 and F9

DIOPT Version :9

Sequence 1:	NP_731802.1	Gene:	CG8870 / 41645	FlyBaseID:	FBgn0038144	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_113728.1	Gene:	F9 / 24946	RGDID:	2589	Length:	462	Species:	Rattus norvegicus

Alignment Length:	394	Identity:	100/394 - (25%)
Similarity:	151/394 - (38%)	Gaps:	129/394 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 GAGCQFDTECVNLDKCPRTRAVMNSSRKNIIGLRRCGTNKVCCPKWETY-LPHD----------T 76
            |..|:.|..|          ::.|...|..  .:....||:.|...|.| |..|          .
  Rat   118 GRNCELDATC----------SIKNGRCKQF--CKNSPDNKIICSCTEGYQLAEDQKSCEPAVPFP 170

  Fly    77 CGQ-----SRRKPTKGKI-------------------------------PALNEF---------- 95
            ||:     :.:|.|:.:.                               ..:|:|
  Rat   171 CGRVSVAYNSKKITRAETVFSNTDYGNSTELILDDITNSTILDNLTENSEPINDFTRVVGGENAK 235

  Fly    96 ----PWMAMLLYGNKNNLSQKLVPKCGGSLINNWYVLTAAHCVEYPFMDYPYALKTVRLGEHNTS 156
                ||..:        |:.::...|||::||..:::|||||::      |.....|..||||..
  Rat   236 PGQIPWQVI--------LNGEIEAFCGGAIINEKWIVTAAHCLK------PGDKIEVVAGEHNID 286

  Fly   157 TNPDRAIVNGRRQYAPLYMEIEVDQIITHEQFNRG-RRLINDIALVRLKFPVRYTRAIQPICLPR 220
            ...|   ...||         .|.:.|.|.|:|.. .:..:||||:.|..|:.....:.|||:
  Rat   287 EKED---TEQRR---------NVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICV-- 337

  Fly   221 AQKLAAHKR------KF---QASGWPDM-GQGIASEVL--LRSFIAERHPDVCKSNYDFNL-GSQ 272
                 |:|.      ||   ..|||..: .:|..:.:|  ||..:.:|  ..|..:..|:: .:.
  Rat   338 -----ANKEYTNIFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVDR--ATCLRSTKFSIYNNM 395

  Fly   273 ICAGGLD-GNDTSPGDSGGPLMETVIRGKVTLTYAAGIISYGQKPCVLKTCKPAFYTKTSYFFEW 336
            .|||..: |.|:..||||||.: |.:.|...||   ||||:|:: |.:|. |...|||.|.:..|
  Rat   396 FCAGYREGGKDSCEGDSGGPHV-TEVEGTSFLT---GIISWGEE-CAMKG-KYGIYTKVSRYVNW 454

  Fly   337 IKSK 340
            ||.|
  Rat   455 IKEK 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8870	NP_731802.1	Tryp_SPc	93..340	CDD:238113	82/275 (30%)
CG8870	NP_731802.1	Tryp_SPc	93..337	CDD:214473	79/272 (29%)
F9	NP_113728.1	GLA	21..85	CDD:214503
		EGF_CA	86..122	CDD:238011	1/3 (33%)
		FXa_inhibition	127..163	CDD:291342	10/47 (21%)
		Tryp_SPc	227..455	CDD:214473	77/268 (29%)
		Tryp_SPc	228..458	CDD:238113	80/270 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910