DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8870 and LOC100004411

DIOPT Version :9

Sequence 1:	NP_731802.1	Gene:	CG8870 / 41645	FlyBaseID:	FBgn0038144	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	XP_001343728.4	Gene:	LOC100004411 / 100004411	-ID:	-	Length:	494	Species:	Danio rerio

Alignment Length:	283	Identity:	77/283 - (27%)
Similarity:	121/283 - (42%)	Gaps:	59/283 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 TCGQSRRKPTKGKIPALNEFPWMAMLL----YGNKNNLSQKLVPKCGGSLINNWYVLTAAHCVEY 136
            |.|....:...|::......||..:|.    ||           .|||||||..:|:|||||::
Zfish   241 TGGNEDTRIVGGQLQRQGGSPWQVLLRREDEYG-----------FCGGSLINQRWVITAAHCLQ- 293

  Fly   137 PFMDYPYALKTVRLGEHNTSTNPDRAIVNGRRQYAPLYMEIEVDQIITHEQFNRGRRLINDIALV 201
               ..|:   .:.:|::: ...||:.           ..:|.|::||.|..::. ....:||||:
Zfish   294 ---QTPH---HITIGDYD-KMRPDKD-----------EQKITVEKIIPHPHYHE-YTFDSDIALL 339

  Fly   202 RLKFPVRYTRAIQPICLP---RAQKLAAHKRKFQASGWPDMGQGIASEVLLRS--FIAERHPDVC 261
            .|...|.......|.|||   .|::|.....:...|||.      ::..|.||  |:.:....|.
Zfish   340 YLSSAVTLGPFASPACLPDANLAERLMKPGEQGLVSGWG------STHYLQRSSRFLRKVQLPVV 398

  Fly   262 KSNYDFNLGSQI------CAGGL-DGNDTSPGDSGGPLMETVIRGKVTLTYAAGIISYGQKPCVL 319
            :.....|...||      |||.| :..|...||||||.:.. .||...||   |::|:|:: |..
Zfish   399 EQKSCINSTEQIITDNMFCAGFLMEEMDACTGDSGGPFIVN-YRGTWFLT---GVVSWGER-CAS 458

  Fly   320 KTCKPAFYTKTSYFFEWIKSKLQ 342
            :. |...||:...:..||:.:::
Zfish   459 QG-KYGVYTRLGNYLSWIQEEMK 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8870	NP_731802.1	Tryp_SPc	93..340	CDD:238113	74/262 (28%)
CG8870	NP_731802.1	Tryp_SPc	93..337	CDD:214473	72/259 (28%)
LOC100004411	XP_001343728.4	GLA	22..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	128..164	CDD:291342
		Tryp_SPc	248..475	CDD:214473	73/269 (27%)
		Tryp_SPc	249..477	CDD:238113	75/270 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920