DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lip3 and MPL1

DIOPT Version :9

Sequence 1:	NP_477331.1	Gene:	Lip3 / 41643	FlyBaseID:	FBgn0023495	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_568295.2	Gene:	MPL1 / 831268	AraportID:	AT5G14180	Length:	418	Species:	Arabidopsis thaliana

Alignment Length:	425	Identity:	135/425 - (31%)
Similarity:	198/425 - (46%)	Gaps:	59/425 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 GALKVTILLVGLGLV--------------------LAGSRPISD-----CGERIEDDGYPMERHE 43
            |::.|..:.:||.|.                    |||..|...     |...:...||..|.|:
plant     3 GSVMVPSVSIGLALSVLIFFALSLKTLEARGTFGRLAGQPPQRTAAGGICASSVHIFGYKCEEHD 67

  Fly    44 VVTSDNYILTMHRIP---YSPKTGESSNRPVAFLMHGMLSSSSDWVLMGPERSLAYMLADAGYDV 105
            |||.|.|||.|.|||   .....|:...|....:.||:|.....|:|...:::|..:|||.|:||
plant    68 VVTQDGYILNMQRIPEGRAGAVAGDGGKRQPVLIQHGILVDGMSWLLNPADQNLPLILADQGFDV 132

  Fly   106 WMGNARGNTYSKAHKYWPTYWQIFWNFSWNEIGMYDVPAMIDYVLAKTGQQQVQYVGHSQGTTVY 170
            ||||.||..:|:.|||.....:.|||::|:|:..||:|||.|::...|| |::.|:|||.||.:.
plant   133 WMGNTRGTRFSRRHKYLNPSQRAFWNWTWDELVSYDLPAMFDHIHGLTG-QKIHYLGHSLGTLIG 196

  Fly   171 LVMVSERPEYNDKIKSAHLLGPAAYMGNM---------KSPLTRAFAPILGQPNAIVEVCGSMEF 226
            ....||: ...|:::||.:|.|.||:.:|         |:.|..| ..|||.|          ||
plant   197 FASFSEK-GLVDQVRSAAMLSPVAYLSHMTTVIGDIAAKTFLAEA-TSILGWP----------EF 249

  Fly   227 MPSNKFKQDLGIEMCQATSPYADMCANEIFLIGGYDTEQLDYELLEHIKATSPAGASVNQNLHFC 291
            .|.:....|....:|....  .| |.:.:.:|.|.:. .|:...::...|..|...|....:|..
plant   250 NPKSGLVGDFIKAICLKAG--ID-CYDLVSVITGKNC-CLNASTIDLFLANEPQSTSTKNMIHLA 310

  Fly   292 QEYNSGKFRKFDY-TALRNPYEYGSYFPPDYKLKNA--KAPVLLYYGANDWMCDVSDVRKLRDEL 353
            |.....:.||::| ::.||...||...||.|.:...  :.|:...||..|.:.||.||..|.|:.
plant   311 QTVRDKELRKYNYGSSDRNIKHYGQAIPPAYNISAIPHELPLFFSYGGLDSLADVKDVEFLLDQF 375

  Fly   354 PNMALDYL-VPFEK-WAHLDFIWGTEARKYVYDEV 386
            ....:|.: |.|.| :||.|||.|..|:..||::|
plant   376 KYHDIDKMNVQFVKDYAHADFIMGVTAKDVVYNQV 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip3	NP_477331.1	PLN02872	26..392	CDD:215470	126/383 (33%)
		Abhydro_lipase	30..89	CDD:282003	22/61 (36%)
		Abhydrolase_5	74..>192	CDD:289465	48/117 (41%)
		Abhydrolase_5	<315..355	CDD:289465	13/41 (32%)
MPL1	NP_568295.2	PLN02872	16..415	CDD:215470	131/412 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D651396at2759
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.970