DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lip3 and LIP1

DIOPT Version :9

Sequence 1:	NP_477331.1	Gene:	Lip3 / 41643	FlyBaseID:	FBgn0023495	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_179126.2	Gene:	LIP1 / 816012	AraportID:	AT2G15230	Length:	393	Species:	Arabidopsis thaliana

Alignment Length:	387	Identity:	116/387 - (29%)
Similarity:	182/387 - (47%)	Gaps:	43/387 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VLAGSRPISDCGERIEDDGYPMERHEVVTSDNYILTMHRI-PYSPKTGESSNRPVAFLMHGMLSS 81
            :|.||...|.|.:.|....|....|.:.|.|.|||.:.|: ...|:.   .:.|...|.||:..:
plant    23 LLHGSPVNSLCADLIHPANYSCTEHSIQTKDGYILALQRVASLGPRL---QSGPPVLLQHGLFMA 84

  Fly    82 SSDWVLMGPERSLAYMLADAGYDVWMGNARGNTYSKAHKYWPTYWQIFWNFSWNEIGMYDVPAMI 146
            ...|.|..|:.||.::|||.|:|||:||.||..||..|.......:.||::||.::.|||:..||
plant    85 GDVWFLNSPKESLGFILADHGFDVWVGNVRGTRYSYGHVTLSDTDKEFWDWSWQDLAMYDLAEMI 149

  Fly   147 DYVLAKTGQQQVQYVGHSQGTTVYLVMVSERPEYNDKIKSAHLLGPAAYMGNMKSPLTRAFAPIL 211
            .| |......::..|||||||.:....::: |...:.:::|.||.|.:|:.::.:||....  :.
plant   150 QY-LYSISNSKIFLVGHSQGTIMSFAALTQ-PHVAEMVEAAALLCPISYLDHVTAPLVERM--VF 210

  Fly   212 GQPNAIVEVCGSMEFMPSNKFKQDLGIE----MCQA--------TSPYADMCANEIFLIGGYDTE 264
            ...:.:|...|..:.    .|:.|:.::    :|:.        ||.....|......|..|
plant   211 MHLDQMVVALGLHQI----NFRSDMLVKLVDSLCEGHMDCTDFLTSITGTNCCFNASKIEYY--- 268

  Fly   265 QLDYELLEHIKATSPAGASVNQNLHFCQEYNSGKFRKFDYTALRNPYEYGSYFPPDYKLKN--AK 327
             ||||         |..:||....|..|....|.|.::||...:|...||...||::.|.:  |.
plant   269 -LDYE---------PHPSSVKNIRHLFQMIRKGTFAQYDYGYFKNLRTYGLSKPPEFILSHIPAS 323

  Fly   328 APVLLYYGANDWMCDVSDVRKLRDELPNM-ALDYLVPFEKWAHLDFIWGTEARKYVYDEVLK 388
            .|:.:.||..|.:.||:||.....|||:. .|.||   |.:.|:||:.|:.|::.||..:::
plant   324 LPMWMGYGGTDGLADVTDVEHTLAELPSSPELLYL---EDYGHIDFVLGSSAKEDVYKHMIQ 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip3	NP_477331.1	PLN02872	26..392	CDD:215470	113/379 (30%)
		Abhydro_lipase	30..89	CDD:282003	16/59 (27%)
		Abhydrolase_5	74..>192	CDD:289465	44/117 (38%)
		Abhydrolase_5	<315..355	CDD:289465	14/41 (34%)
LIP1	NP_179126.2	PLN02872	6..393	CDD:215470	116/387 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D651396at2759
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.970