DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lip3 and CG2772

DIOPT Version :9

Sequence 1:	NP_477331.1	Gene:	Lip3 / 41643	FlyBaseID:	FBgn0023495	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_608776.1	Gene:	CG2772 / 33559	FlyBaseID:	FBgn0031533	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	379	Identity:	167/379 - (44%)
Similarity:	215/379 - (56%)	Gaps:	21/379 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 ERIEDDGYPMERHEVVTSDNYILTMHRIPYSPK------TGES-SNRPVAFLMHGMLSSSSDWVL 87
            |||.:.|||.|.|.|.|.|.|:|.:.|||:|||      .||| ::|||..:|||:.|.|..::|
  Fly    37 ERIAEHGYPAESHFVETPDGYVLNVFRIPHSPKLNSNGNEGESEASRPVVLIMHGLFSCSDCFLL 101

  Fly    88 MGPERSLAYMLADAGYDVWMGNARGNTYSK-------AHKYWPTYWQIFWNFSWNEIGMYDVPAM 145
            .|||.:|.|..||||||||:||||||.||:       .|.|       ||.|||:|||..|:||.
  Fly   102 NGPEDALPYNYADAGYDVWLGNARGNIYSRNNTRLNVKHPY-------FWKFSWHEIGSIDLPAT 159

  Fly   146 IDYVLAKTGQQQVQYVGHSQGTTVYLVMVSERPEYNDKIKSAHLLGPAAYMGNMKSPLTRAFAPI 210
            |||:||:||||.:.|||||||.|.:.||.|.|||||.|||:||:|.|..||||....|..:.||:
  Fly   160 IDYILAETGQQSLHYVGHSQGCTSFFVMGSYRPEYNAKIKTAHMLAPPVYMGNSTEGLIVSTAPL 224

  Fly   211 LGQPNAIVEVCGSMEFMPSNKFKQDLGIEMCQATSPYADMCANEIFLIGGYDTEQLDYELLEHIK 275
            .|.......:..:...:|.|.|.|.:....|.........|.....|.||.:...|:..||..|.
  Fly   225 FGHHGIGSTLLENQVLLPQNAFIQRVLDTTCSNQPIMLSYCKTLAILWGGPEIGNLNQTLLPQIA 289

  Fly   276 ATSPAGASVNQNLHFCQEYNSGKFRKFDYTALRNPYEYGSYFPPDYKLKNAKAPVLLYYGANDWM 340
            .|.|||.|.||.:|:.|.|.|..||.:|:.:.||...||...||.|.|....:.:.||||..|..
  Fly   290 ETHPAGVSSNQAIHYIQSYASNDFRLYDWGSKRNLEYYGVSEPPAYDLTKITSELYLYYGLADGS 354

  Fly   341 CDVSDVRKLRDELPNMALDYLVPFEKWAHLDFIWGTEARKYVYDEVLKQMQSYE 394
            .:..|:.:|.|.|||:||.:.||...|.|||||:.||.::.:.|.||...::|:
  Fly   355 ANKQDISRLPDLLPNLALLHEVPDSTWGHLDFIFATEVKRVINDLVLDYSKAYD 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip3	NP_477331.1	PLN02872	26..392	CDD:215470	166/375 (44%)
		Abhydro_lipase	30..89	CDD:282003	31/65 (48%)
		Abhydrolase_5	74..>192	CDD:289465	71/124 (57%)
		Abhydrolase_5	<315..355	CDD:289465	13/39 (33%)
CG2772	NP_608776.1	PLN02872	5..393	CDD:215470	163/362 (45%)
		Abhydro_lipase	36..103	CDD:282003	31/65 (48%)
		Abhydrolase	113..>196	CDD:304388	53/89 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471666
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	11	10.800