DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lip3 and SPCC1672.09

DIOPT Version :9

Sequence 1:	NP_477331.1	Gene:	Lip3 / 41643	FlyBaseID:	FBgn0023495	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_587880.1	Gene:	SPCC1672.09 / 2539344	PomBaseID:	SPCC1672.09	Length:	467	Species:	Schizosaccharomyces pombe

Alignment Length:	383	Identity:	115/383 - (30%)
Similarity:	186/383 - (48%)	Gaps:	41/383 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 SDCGERIEDDGYPMERHEVVTSDNYILTMHRI----------PYSPKTGESSNRPVAFLMHGMLS 80
            :|..|..:..||.:|.|.|.|.|:|||.:|||          |:..|.      ||.:..||:|.
pombe    79 ADIREMCKISGYYVEDHLVRTEDDYILCIHRISKDSPGRIGSPHPKKL------PVVYCHHGLLM 137

  Fly    81 SSSDWVL-MGPERSLAYMLADAGYDVWMGNARGNTYSKAHKYWPTYWQIFWNFSWNEIGMYDVPA 144
            :|..||. :.|...|.:.|.:.|||||:||.|||.||:.|..:.:..:.||:||.::...||:|.
pombe   138 NSEVWVCNVDPRNCLVFDLVNKGYDVWLGNNRGNKYSRQHLRFDSTDKEFWDFSIDDFAQYDIPD 202

  Fly   145 MIDYVLAKTGQQQVQYVGHSQGTTVYLVMVSERPEYNDKIKSAHLLGPAAYMGNMKSPLTRAFAP 209
            .|||:|..:||.::.|:|.||||......:|..|..||||.|...|.||.....:.:.:..||
pombe   203 TIDYILKTSGQTKLTYIGFSQGTAQAFASLSIHPLLNDKINSLIALAPAISPKGLHNRVVDAF-- 265

  Fly   210 ILGQPNAIVEVCGSMEFMPSNKFKQD-LGIEMCQATSPYADMCANEIFLIGGYDTEQL-DYELL- 271
            :..:|:.:..:.|....:||..|.|. |..:...|...|   |.:::|   .:..:.: .|:.|
pombe   266 VKARPSILFFLFGRKSILPSAGFWQSFLAPKFFDAVLAY---CLSQLF---NWSCQNISSYQRLV 324

  Fly   272 --EHIKATSPAGASVNQNLHFCQEYNSGKFRKFDYTALRNPYEYGSYFPPDYKLKNAKAPVLLYY 334
              .|:.:.:    ||...:|:.|...|.:||.:|...|.:.|....|....:...|.:.|:.|.:
pombe   325 SFAHLYSYT----SVKCLVHWFQIMRSAEFRMYDNDQLGHDYFLKYYKAAKFPTNNIRTPIYLIW 385

  Fly   335 GANDWMCDV-SDVRKLRDELPNMALDYLVPFEKWAHLDFIWGTEARKYVYDEVLKQMQ 391
            |.:|.:.|: :.:..|..|:.::.:|      .:.|||.||....:.||...||::::
pombe   386 GGSDSLVDIQAMLNALPAEVEHVKVD------SYEHLDMIWADTVKDYVIPPVLRRLR 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip3	NP_477331.1	PLN02872	26..392	CDD:215470	115/383 (30%)
		Abhydro_lipase	30..89	CDD:282003	24/69 (35%)
		Abhydrolase_5	74..>192	CDD:289465	49/118 (42%)
		Abhydrolase_5	<315..355	CDD:289465	9/40 (23%)
SPCC1672.09	NP_587880.1	Abhydro_lipase	81..145	CDD:282003	24/69 (35%)
SPCC1672.09	NP_587880.1	Abhydrolase_1	127..422	CDD:278959	94/312 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm9260
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1506
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	11	10.800