Protein Alignment Dic1 and SLC25A14

DIOPT Version :9

• Sequence 1: NP_001287313.1
• Gene: Dic1 / 41640
• FlyBaseID: FBgn0027610
• Length: 280
• Species: Drosophila melanogaster
• Sequence 2: NP_001269126.1
• Gene: SLC25A14 / 9016
• HGNCID: 10984
• Length: 353
• Species: Homo sapiens
• Alignment Length: 324
• Identity: 83/324 - (25%)
• Similarity: 142/324 - (43%)
• Gaps: 79/324 - (24%)

  Fly    12 FGGLASVGAAMVTHPLDLIKVTLQTQQGHL----------SVAQLIPKLAREQGVLVFYNGLSAS 66
            :|||||:.|...|.|:||.|..||.|...:          .:...:.::.:|:|||..|:|::.:
Human    43 YGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPA 107

  Fly    67 VLRQLTYSTARFGVYEAGKKY----VNTDSFGGKVALAGASGLVGGIVGTPADMVNVRMQNDVKL 127
            :|||.:|.|.:.|:|::.|:.    :..::....:.....||::...:..|.|::.:|||....|
Human   108 LLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSL 172

  Fly   128 PPQQRRNYNNAFDG-----LVRVYRQEGFKRLF-------------------------------S 156
                       |.|     .:.:|:|||.:.|:                               .
Human   173 -----------FQGSMIGSFIDIYQQEGTRGLWRCLCSKAVTGCVLWLMPVIPALWEANAGGSLE 226

  Fly   157 GATAATARGILMTIGQIAFYDQTKIYLLATPYFQDNLVTHFTASLVAGTIATTLTQPLDVLKTRS 221
            |......|..::...::..||.||.:|:.:....|.::|||.:|...|......:.|:||::||.
Human   227 GVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRM 291

  Fly   222 MNAK---------PGEFNGLWDIVKHTAKLGPLGFF---KGYVPAFVRLGPHTIITFVFLEQLR 273
            ||.:         .|..:|:..:.||.      |||   ||:.|.::||||..||.|:..|||:
Human   292 MNQRAIVGHVDLYKGTVDGILKMWKHE------GFFALYKGFWPNWLRLGPWNIIFFITYEQLK 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dic1	NP_001287313.1	Mito_carr	10..92	CDD:278578	28/93 (30%)
		PTZ00169	13..273	CDD:240302	82/321 (26%)
		Mito_carr	89..184	CDD:278578	21/130 (16%)
		Mito_carr	189..278	CDD:278578	33/97 (34%)
SLC25A14	NP_001269126.1	Mito_carr	37..133	CDD:278578	28/89 (31%)
		PTZ00169	41..351	CDD:240302	83/324 (26%)
		Mito_carr	134..254	CDD:278578	21/130 (16%)
		Mito_carr	262..351	CDD:278578	32/94 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R857
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840