Protein Alignment Dic1 and Slc25a27

DIOPT Version :10

• Sequence 1: NP_650279.1
• Gene: Dic1 / 41640
• FlyBaseID: FBgn0027610
• Length: 280
• Species: Drosophila melanogaster
• Sequence 2: XP_017173167.1
• Gene: Slc25a27 / 74011
• MGIID: 1921261
• Length: 344
• Species: Mus musculus
• Alignment Length: 298
• Identity: 83/298 - (27%)
• Similarity: 140/298 - (46%)
• Gaps: 49/298 - (16%)

  Fly    22 MVTHPLDLIKVTLQTQQGHLSVAQL-------IP---------KLAREQGVLVFYNGLSASVLRQ 70
            :.|.||||.|..|| .||..::|:|       .|         .:.:|:|.|..:.|::.::.|.
Mouse    48 LTTFPLDLTKTRLQ-MQGEAALARLGDGAVDSAPYRGMVRTALGIVQEEGFLKLWQGVTPAIYRH 111

  Fly    71 LTYSTARFGVYEAGKKYVNTDS-----------FGGKVALAGASGLVGGIVGTPADMVNVRMQND 124
            :.||..|...||..::.|...|           .||.:|     |::|..:..|.|:|.|:||.:
Mouse   112 VVYSGGRMVTYEHLREVVFGKSEDKHYPLWKSVIGGMMA-----GVIGQFLANPTDLVKVQMQME 171

  Fly   125 VKL----PPQQRRNYNNAFDGLVRVYRQEGFKRLFSGATAATARGILMTIGQIAFYDQTKIYLLA 185
            .|.    .|.:.|..::||   .::..:.|.:.|::|......|..|:.:|.:..||..|.||:.
Mouse   172 GKRRLEGKPLRFRGVHHAF---AKILAEGGIRGLWAGWIPNIQRAALVNMGDLTTYDTVKHYLVL 233

  Fly   186 TPYFQDNLVTHFTASLVAGTIATTLTQPLDVLKTRSMNAKPGEFNGLWDIVKHTAKL-------- 242
            ....:||:.||..:||.:|.:|:.|..|.||:|:|.|| :|.:..|...:.|.:|..
Mouse   234 NTPLEDNISTHGLSSLCSGLVASILGTPADVIKSRIMN-QPRDKQGRGLLYKSSADCLIQAVQGE 297

  Fly   243 GPLGFFKGYVPAFVRLGPHTIITFVFLEQLRLKFGTLN 280
            |.|..:||::|:::|:.....:.|:.|....|.|..|:
Mouse   298 GFLSLYKGFLPSWLRMVKMGEVLFLPLLLFSLYFSYLS 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dic1	NP_650279.1	Mito_carr	10..92	CDD:395101	24/85 (28%)
		Mito_carr	89..184	CDD:395101	27/109 (25%)
		Mito_carr	189..278	CDD:395101	30/96 (31%)
Slc25a27	XP_017173167.1	Mito_carr	<48..133	CDD:395101	24/85 (28%)
		Mito_carr	136..232	CDD:395101	26/103 (25%)
		Mito_carr	238..>314	CDD:395101	26/76 (34%)