Protein Alignment Dic1 and Slc25a35

DIOPT Version :10

• Sequence 1: NP_650279.1
• Gene: Dic1 / 41640
• FlyBaseID: FBgn0027610
• Length: 280
• Species: Drosophila melanogaster
• Sequence 2: NP_082324.1
• Gene: Slc25a35 / 71998
• MGIID: 1919248
• Length: 300
• Species: Mus musculus
• Alignment Length: 300
• Identity: 77/300 - (25%)
• Similarity: 136/300 - (45%)
• Gaps: 36/300 - (12%)

  Fly    10 WFFGGLASVGAAMVTHPLDLIKVTLQ---------TQQGHL-SVAQLIPKLAREQGVLVFYNGLS 64
            :...|:|:.||.:.|:||:::|..:|         |.|.|. :|......:.:..|:.....||.
Mouse     3 FLMSGVAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFFTIGKVDGLAALQKGLG 67

  Fly    65 ASVLRQLTYSTARFGVY--EAGKKYVNTDSFGG-----KVALAGA-SGLVGGIVGTPADMVNVRM 121
            .::|.|...:..|.|.|  ...:.|::|:.  |     :.|.||| :|::|..:|:|..||...:
Mouse    68 PALLYQFLMNGIRLGTYGLAESRGYLHTNE--GTHSPVRSAAAGALAGVMGAYLGSPIYMVKTHL 130

  Fly   122 Q----NDVKLPPQQRRNYNNAFDGLVRVYRQEGFKRLFSGATAATARGILMTIGQIAFYDQTKIY 182
            |    :::.:..|.:  :...|..|..:.::.|...|:.||.....|.::.:..|:..:...|..
Mouse   131 QAQAASEIAVGHQYK--HQGMFQALTEIGQKHGLVGLWRGAVGGLPRVVIGSSTQLCTFSSIKDL 193

  Fly   183 LLATPYF-QDNLVTHFTASLVAGTIATTLTQPLDVLKTRSMNAKPGE-------FNGLWDIVKHT 239
            |.....| ..:......|::|:|........|.||..||..| :|.:       :.|:.|.:..|
Mouse   194 LSQWEIFPPQSWKVALAAAMVSGVAIVVAMTPFDVASTRLYN-QPTDTRGKGLMYRGILDALLQT 257

  Fly   240 AKL-GPLGFFKGYVPAFVRLGPHTIITFVFLEQLRLKFGT 278
            |:. |..|.:||...::.|||||||::..|.:|||..:.|
Mouse   258 ARTEGFFGMYKGIGASYFRLGPHTILSLFFWDQLRSFYNT 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dic1	NP_650279.1	Mito_carr	10..92	CDD:395101	23/93 (25%)
		Mito_carr	89..184	CDD:395101	23/104 (22%)
		Mito_carr	189..278	CDD:395101	30/97 (31%)
Slc25a35	NP_082324.1	Solcar 1	1..90		21/86 (24%)
		Mito_carr	2..84	CDD:395101	20/80 (25%)
		Mito_carr	98..195	CDD:395101	22/98 (22%)
		Solcar 2	100..193		21/94 (22%)
		Solcar 3	203..294		29/91 (32%)
		Mito_carr	209..298	CDD:395101	29/89 (33%)