DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dic1 and slc25a35

DIOPT Version :9

Sequence 1:NP_001287313.1 Gene:Dic1 / 41640 FlyBaseID:FBgn0027610 Length:280 Species:Drosophila melanogaster
Sequence 2:NP_001092917.1 Gene:slc25a35 / 557185 ZFINID:ZDB-GENE-060526-142 Length:298 Species:Danio rerio


Alignment Length:296 Identity:78/296 - (26%)
Similarity:139/296 - (46%) Gaps:39/296 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 WFFGGLASVGAAMVTHPLDLIKVTLQTQQGHL-----------SVAQLIPKLAREQGVLVFYNGL 63
            :..||:|:.||...|:||:::|..:|. ||.|           :|......:.:..|:.....||
Zfish     3 FILGGVAACGACFFTNPLEVVKTRMQL-QGELKSRGTYQVYYRNVFHAFYTIGKIDGLAGLQKGL 66

  Fly    64 SASVLRQLTYSTARFGVYEAGKK--YVNTDSFGGKVA-----LAGA-SGLVGGIVGTPADMVNVR 120
            ...::.|...:..|.|.|...:.  |::||   |:|:     ::|| :|:||.::|:|..:|...
Zfish    67 VPGLVYQFFMNGVRLGSYALTESLGYIHTD---GRVSATKSTVSGAIAGVVGAVMGSPIYLVKTH 128

  Fly   121 MQ----NDVKLPPQ-QRRNYNNAFDGLVRVYRQEGFKRLFSGATAATARGILMTIGQIAFYDQTK 180
            :|    :.:.:..| :.|...||   |..:::|.|...|:.||:||..|..:.:..|:|.:..:|
Zfish   129 LQSQSTSSIAVGHQYKHRGMTNA---LFAIHKQHGILGLWRGASAAIPRVSVGSAAQLATFSASK 190

  Fly   181 IYLLATPYFQD-NLVTHFTASLVAGTIATTLTQPLDVLKTRSMN------AKPGEFNGLWDIVKH 238
            ..:.....|.: :.:...:|.:::..:......|.||:.||..|      .|...:.|..|....
Zfish   191 EMVNDLQVFSEGSWLIALSAGMISSVVVVLAMTPFDVVSTRLYNQPVDHLGKGMLYRGFVDCFSK 255

  Fly   239 TAKL-GPLGFFKGYVPAFVRLGPHTIITFVFLEQLR 273
            |.|. |..|.:||...::.|||||||::.:|..:||
Zfish   256 TLKKEGMTGLYKGLGASYFRLGPHTILSLLFWNELR 291

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dic1NP_001287313.1 Mito_carr 10..92 CDD:278578 23/94 (24%)
PTZ00169 13..273 CDD:240302 76/291 (26%)
Mito_carr 89..184 CDD:278578 29/105 (28%)
Mito_carr 189..278 CDD:278578 27/93 (29%)
slc25a35NP_001092917.1 Solcar 1 1..90 21/87 (24%)
PTZ00169 2..291 CDD:240302 76/294 (26%)
Mito_carr 2..84 CDD:278578 20/81 (25%)
Mito_carr 97..195 CDD:278578 27/100 (27%)
Solcar 2 99..192 26/95 (27%)
Mito_carr 200..286 CDD:278578 23/85 (27%)
Solcar 3 202..293 26/90 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R857
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.940

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