DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dic1 and oac1

DIOPT Version :9

Sequence 1:	NP_001287313.1	Gene:	Dic1 / 41640	FlyBaseID:	FBgn0027610	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_593169.1	Gene:	oac1 / 2541790	PomBaseID:	SPAC139.02c	Length:	320	Species:	Schizosaccharomyces pombe

Alignment Length:	304	Identity:	98/304 - (32%)
Similarity:	145/304 - (47%)	Gaps:	30/304 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PHQERK----SMWFFGGLASVGAAMVTHPLDLIKVTLQTQQGHL-----------SVAQLIPKLA 51
            |.|.:|    |.:..||||:.||..:|:|.::||...|. ||.|           ||.|....:|
pombe    15 PTQVKKLGPVSGFLSGGLAACGAVTLTNPFEVIKTRFQL-QGQLTKLDPSKRIYKSVGQAFSLIA 78

  Fly    52 REQGVLVFYNGLSASVLRQLTYSTARFGVYEAGKKYVNT----DSFGGKVAL---AGA-SGLVGG 108
            |.:|:.....||..:.:.|:..:..|.|.||..::.:||    |..|.|:|:   :|| |||.|.
pombe    79 RHEGIRGLQRGLGTAYVYQICLNGCRLGFYEPIRRTLNTWFLDDPKGNKLAINVASGAGSGLCGA 143

  Fly   109 IVGTPADMVNVRMQN-DVKLPPQQRRNYNNAFDGLVRVYRQEGFKRLFSGATAATARGILMTIGQ 172
            :.|:|..:|..|||: ..|.|..|:..|.:.|:...|:.::.|.|.||.||.||..|.:..:..|
pombe   144 LFGSPFFLVKTRMQSYSPKFPVGQQYGYKHIFNAFSRIIKENGVKGLFVGADAAILRTVSGSSVQ 208

  Fly   173 IAFYDQTKIYLLATPYFQDNLVTHFTASLVAGTIATTLTQPLDVLKTRSMNAKPGEF--NGLWDI 235
            :..|:..|..:......::.::.|.|||.|:|.......|..|.:.||..|.|..|.  |.:..|
pombe   209 LPIYNWAKRMIEHYNLLEEGMIKHLTASAVSGFGVCCTMQIFDTVMTRMYNQKNKELYKNPIDCI 273

  Fly   236 VKHTAKLGPLGFFKGYVPAFVRLGPHTIITFVFLEQ---LRLKF 276
            :|.....|....:||:.....|:.||||....|:||   |.|||
pombe   274 LKTIRSEGFFALYKGFGAHLARIAPHTIFCLTFVEQTNKLFLKF 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dic1	NP_001287313.1	Mito_carr	10..92	CDD:278578	29/96 (30%)
		PTZ00169	13..273	CDD:240302	90/284 (32%)
		Mito_carr	89..184	CDD:278578	36/103 (35%)
		Mito_carr	189..278	CDD:278578	31/93 (33%)
oac1	NP_593169.1	PTZ00169	19..295	CDD:240302	84/276 (30%)
		Mito_carr	19..117	CDD:278578	29/98 (30%)
		Mito_carr	127..223	CDD:278578	32/95 (34%)
		Mito_carr	226..316	CDD:278578	28/89 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R857
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940