DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Dic1 and SLC25A30

DIOPT Version :9

Sequence 1:NP_001287313.1 Gene:Dic1 / 41640 FlyBaseID:FBgn0027610 Length:280 Species:Drosophila melanogaster
Sequence 2:XP_005266378.1 Gene:SLC25A30 / 253512 HGNCID:27371 Length:293 Species:Homo sapiens


Alignment Length:229 Identity:63/229 - (27%)
Similarity:111/229 - (48%) Gaps:22/229 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 FGGLASVGAAMVTHPLDLIKVTLQTQQGHLSVAQL-----------IPKLAREQGVLVFYNGLSA 65
            :|||||:.|...|.|:||.|..||. ||..:.|:.           :.::.||:|:...|:|::.
Human    11 YGGLASITAECGTFPIDLTKTRLQI-QGQTNDAKFKEIRYRGMLHALVRIGREEGLKALYSGIAP 74

  Fly    66 SVLRQLTYSTARFGVYEAGKKYV----NTDSFGGKVALAGASGLVGGIVGTPADMVNVRMQNDVK 126
            ::|||.:|.|.:.|.|::.|:..    ..::....|.....||::...:..|.|::.:|||    
Human    75 AMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIANPTDVLKIRMQ---- 135

  Fly   127 LPPQQRRNYNNAFDGLVRVYRQEGFKRLFSGATAATARGILMTIGQIAFYDQTKIYLLATPYFQD 191
              .|............:.:|:|||.:.|:.|.:....|..::...::..||.||.:|:.:....|
Human   136 --AQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGD 198

  Fly   192 NLVTHFTASLVAGTIATTLTQPLDVLKTRSMNAK 225
            .:.|||.:|...|......:.|:||::||.||.:
Human   199 TVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQR 232

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dic1NP_001287313.1 Mito_carr 10..92 CDD:278578 29/94 (31%)
PTZ00169 13..273 CDD:240302 63/228 (28%)
Mito_carr 89..184 CDD:278578 20/94 (21%)
Mito_carr 189..278 CDD:278578 13/37 (35%)
SLC25A30XP_005266378.1 Mito_carr 5..100 CDD:278578 29/89 (33%)
Mito_carr 102..191 CDD:278578 20/94 (21%)
Mito_carr 199..>252 CDD:278578 12/34 (35%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0759
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R857
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.840

Return to query results.
Submit another query.