DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dic1 and Ucp2

DIOPT Version :9

Sequence 1:NP_001287313.1 Gene:Dic1 / 41640 FlyBaseID:FBgn0027610 Length:280 Species:Drosophila melanogaster
Sequence 2:NP_035801.3 Gene:Ucp2 / 22228 MGIID:109354 Length:309 Species:Mus musculus


Alignment Length:289 Identity:92/289 - (31%)
Similarity:143/289 - (49%) Gaps:36/289 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 FFG-GLASVGAAMVTHPLDLIKVTLQTQ---QG---------HLSVAQLIPKLAREQGVLVFYNG 62
            |.| |.|:..|.::|.|||..||.||.|   ||         :..|...|..:.|.:|....|||
Mouse    17 FLGAGTAACIADLITFPLDTAKVRLQIQGESQGLVRTAASAQYRGVLGTILTMVRTEGPRSLYNG 81

  Fly    63 LSASVLRQLTYSTARFGVYEAGKKYVNTDS----FGGKVALAGASGLVGGIVGTPADMVNVRMQN 123
            |.|.:.||:::::.|.|:|::.|::....|    .|.::.....:|.:...|..|.|:|.||.| 
Mouse    82 LVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAGIGSRLLAGSTTGALAVAVAQPTDVVKVRFQ- 145

  Fly   124 DVKLPPQQR----RNYNNAFDGLVRVYRQEGFKRLFSGATAATARGILMTIGQIAFYDQTKIYLL 184
                 .|.|    |.|.:..:....:.|:||.:.|:.|.:...||..::...::..||..|..||
Mouse   146 -----AQARAGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPNVARNAIVNCAELVTYDLIKDTLL 205

  Fly   185 ATPYFQDNLVTHFTASLVAGTIATTLTQPLDVLKTRSMNAKPGEFNGLWDIVKHTA-----KLGP 244
            ......|:|..|||::..||...|.:..|:||:|||.||:..|:::.    ..|.|     |.||
Mouse   206 KANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYHS----AGHCALTMLRKEGP 266

  Fly   245 LGFFKGYVPAFVRLGPHTIITFVFLEQLR 273
            ..|:||::|:|:|||...::.||..|||:
Mouse   267 RAFYKGFMPSFLRLGSWNVVMFVTYEQLK 295

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dic1NP_001287313.1 Mito_carr 10..92 CDD:278578 31/93 (33%)
PTZ00169 13..273 CDD:240302 90/285 (32%)
Mito_carr 89..184 CDD:278578 24/102 (24%)
Mito_carr 189..278 CDD:278578 35/90 (39%)
Ucp2NP_035801.3 Mito_carr 11..109 CDD:365909 31/91 (34%)
Solcar 1 11..106 31/88 (35%)
Solcar 2 114..203 23/94 (24%)
Mito_carr 115..206 CDD:365909 24/96 (25%)
Solcar 3 212..297 35/88 (40%)
Mito_carr 217..299 CDD:365909 33/83 (40%)
Purine nucleotide binding. /evidence=ECO:0000250 276..298 9/20 (45%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0759
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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