DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dic1 and slc25a10a

DIOPT Version :9

Sequence 1:	NP_001287313.1	Gene:	Dic1 / 41640	FlyBaseID:	FBgn0027610	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_002661286.1	Gene:	slc25a10a / 100332610	ZFINID:	ZDB-GENE-131127-11	Length:	288	Species:	Danio rerio

Alignment Length:	280	Identity:	150/280 - (53%)
Similarity:	194/280 - (69%)	Gaps:	7/280 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QERKSMWFFGGLASVGAAMVTHPLDLIKVTLQTQQG-HLSVAQLIPKLAREQGVLVFYNGLSASV 67
            :.|.|.|:|||:||..||..|||||||||.|||||. .:.:..:..::.|..||...|||||||:
Zfish     3 ETRVSRWYFGGIASCAAACCTHPLDLIKVHLQTQQEVKMRMTGMAVQVVRSDGVFALYNGLSASL 67

  Fly    68 LRQLTYSTARFGVYEAGKKYVNTDS-----FGGKVALAGASGLVGGIVGTPADMVNVRMQNDVKL 127
            .||::||..||.:||..:..:.:.:     |..|:.||...|..||.:||||||||||||||:||
Zfish    68 CRQMSYSMTRFAIYETVRDQIASQNQGPMPFYQKILLAAFGGFTGGFIGTPADMVNVRMQNDMKL 132

  Fly   128 PPQQRRNYNNAFDGLVRVYRQEGFKRLFSGATAATARGILMTIGQIAFYDQTKIYLLATPYFQDN 192
            ||..||||.:|.|||:||.::||.::|||||:.|.:||.|:|:||::.|||.|..:|.|....||
Zfish   133 PPVLRRNYAHALDGLLRVLKEEGIRKLFSGASMAASRGALVTVGQLSCYDQAKQLVLGTGLMTDN 197

  Fly   193 LVTHFTASLVAGTIATTLTQPLDVLKTRSMNAKPGEFNGLWDIVKHTAKLGPLGFFKGYVPAFVR 257
            :.|||.||.:||..||.|.||:||:|||.||:| ||:.||...:..|.||||..|:||.|||.:|
Zfish   198 IFTHFVASFIAGGCATVLCQPMDVVKTRLMNSK-GEYRGLIHCLSDTGKLGPKAFYKGLVPAGIR 261

  Fly   258 LGPHTIITFVFLEQLRLKFG 277
            |.|||::||:|||||||.||
Zfish   262 LIPHTVLTFIFLEQLRLYFG 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dic1	NP_001287313.1	Mito_carr	10..92	CDD:278578	40/82 (49%)
		PTZ00169	13..273	CDD:240302	141/265 (53%)
		Mito_carr	89..184	CDD:278578	53/99 (54%)
		Mito_carr	189..278	CDD:278578	53/89 (60%)
slc25a10a	XP_002661286.1	Mito_carr	12..86	CDD:278578	38/73 (52%)
		Mito_carr	94..190	CDD:278578	53/95 (56%)
		Mito_carr	195..281	CDD:278578	51/86 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594900
Domainoid	1	1.000	121	1.000	Domainoid score	I5647
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	300	1.000	Inparanoid score	I2665
OMA	1	1.010	-	-		QHG51917
OrthoDB	1	1.010	-	-		D404074at33208
OrthoFinder	1	1.000	-	-		FOG0002037
OrthoInspector	1	1.000	-	-		mtm6385
orthoMCL	1	0.900	-	-		OOG6_104245
Panther	1	1.100	-	-	O	PTHR45618
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1953
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770