DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PK2-R1 and Nmur1

DIOPT Version :9

Sequence 1:	NP_731790.1	Gene:	PK2-R1 / 41639	FlyBaseID:	FBgn0038140	Length:	660	Species:	Drosophila melanogaster
Sequence 2:	XP_017452122.1	Gene:	Nmur1 / 65276	RGDID:	619867	Length:	414	Species:	Rattus norvegicus

Alignment Length:	434	Identity:	147/434 - (33%)
Similarity:	212/434 - (48%)	Gaps:	79/434 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 NPSESPEMLLLKNDKFLTHV-AHLLNITTENLS-NLLGSTNGTNASTMAADSPVDESLTLRTALT 111
            :|:.|..:|...:.:|..|. ...||:|.|:|. ..||...                  ::..|.
  Rat     5 SPNASTGLLSCNDSEFKEHFDLEDLNLTHEDLRLKYLGPQQ------------------VKQFLP 51

  Fly   112 VC--YALIFVAGVLGNLITCIVISRNNFMHTATNFYLFNLAVSDLILLVSGIPQELYNLWYPDMY 174
            :|  |.||||.|.|||.:||.||.|...|||.||||||:||||||::|:.|:|.|||.:.:  .|
  Rat    52 ICVTYLLIFVVGTLGNGLTCTVILRQKAMHTPTNFYLFSLAVSDLLVLLVGLPLELYEMQH--NY 114

  Fly   175 PFT--DAMCIMGSVLSEMAANATVLTITAFTVERYIAICHPFRQHTMSKLSRAIKFIFAIWLAAF 237
            ||.  ...|....:|.|....|:||.:||.:||||:|:.||.:..::...:...:.:.|||:.|.
  Rat   115 PFQLGAGGCYFRILLLETVCLASVLNVTALSVERYVAVVHPLQAKSVMTRTHVRRMLGAIWVFAI 179

  Fly   238 LLALPQAM--QFSVVY------QNEGYSCTMEND--FYAHVFAVSGFIFFGGPMTAICVLYVLIG 292
            |.:||...  ..|.:|      ..:..:||:...  ||..|...:..:||..||..|.|||:|||
  Rat   180 LFSLPNTSLHGLSPLYVPCRGPVPDSVTCTLVRPQFFYKLVIQTTILLFFCLPMVTISVLYLLIG 244

  Fly   293 VKLKRSR-LLQSLPRRTFDA------NRGLNAQGR----VIRMLVAVAVAFFLCWAPFHAQRLM- 345
            ::|:|.| |||...:....|      :|.:..:.|    |.:||:|:.:.|..||.||||.|||
  Rat   245 LRLRRERILLQEEVKGRISAAARQASHRSIQLRDRERRQVTKMLIALVIVFGTCWVPFHADRLMW 309

  Fly   346 -----AVYGLNLINIGISRDAFNDYFRILDYTSGVLYFLSTCINPLLYNIMSHKFREAFKITLTR 405
                 ...||.|.            |:.:...|||..:|.:..||:|||:||.:|||:|:.||
  Rat   310 SMVSHWTDGLRLA------------FQSVHLASGVFLYLGSAANPVLYNLMSTRFRESFRETL-- 360

  Fly   406 QFGL-ARNHHHQQSQHHQHNYSALLRQNGSMRLQPASCSVNNNA 448
              || .|..|..|.:|..|::         :||...|...:.|:
  Rat   361 --GLGTRCCHRHQPRHDSHSH---------LRLTTVSTLCDRNS 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R1	NP_731790.1	7tm_4	114..>242	CDD:304433	58/129 (45%)
PK2-R1	NP_731790.1	7tm_1	124..388	CDD:278431	104/292 (36%)
Nmur1	XP_017452122.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338873
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BGH7
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380940at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8974
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24243
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X673
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.810