DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PK2-R1 and Nmur2

DIOPT Version :9

Sequence 1:	NP_731790.1	Gene:	PK2-R1 / 41639	FlyBaseID:	FBgn0038140	Length:	660	Species:	Drosophila melanogaster
Sequence 2:	NP_071611.3	Gene:	Nmur2 / 64042	RGDID:	621155	Length:	395	Species:	Rattus norvegicus

Alignment Length:	427	Identity:	127/427 - (29%)
Similarity:	201/427 - (47%)	Gaps:	73/427 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 LNITTENLSNLLGSTNGTNASTMAADSPVDESLTLRTALTVCYALIFVAGVLGNLITCIVISRNN 136
            ||.|.|.|::|.|              |....|:|  .::|.|||||:.||:|||:.|:||.|:.
  Rat    18 LNSTEEYLAHLCG--------------PKRSDLSL--PVSVAYALIFLVGVMGNLLVCMVIVRHQ 66

  Fly   137 FMHTATNFYLFNLAVSDLILLVSGIPQELYNLWYPDMYPFTDAMCIMGSVLSEMAANATVLTITA 201
            .:.|.||:|||:||||||::|:.|:|.|:|.:|:...:.|....|...:.|.|....|::|::|.
  Rat    67 TLKTPTNYYLFSLAVSDLLVLLLGMPLEIYEMWHNYPFLFGPVGCYFKTALFETVCFASILSVTT 131

  Fly   202 FTVERYIAICHPFRQHTMSKLSRAIKFIFAIWLAAFLLALPQAMQFSVVYQN--EGYS------C 258
            .:||||:||.||||....|...||::.:..:|..:.:.:||......:.:|:  .|.|      |
  Rat   132 VSVERYVAIVHPFRAKLESTRRRALRILSLVWSFSVVFSLPNTSIHGIKFQHFPNGSSVPGSATC 196

  Fly   259 TMENDFYAH--VFAVSGFIFFGGPMTAICVLYVLIGVKLKRSRLLQSLPRRTFDANRGLNAQGRV 321
            |:....:.:  :...:.|:|:..|||.|.|||.|:|::|||.   :||.......|....::..|
  Rat   197 TVTKPMWVYNLIIQATSFLFYILPMTLISVLYYLMGLRLKRD---ESLEANKVAVNIHRPSRKSV 258

  Fly   322 IRMLVAVAVAFFLCWAPFHAQRLMAVYGLNLINIGISRDAFNDYFRILDYTSGVLYFLSTCINPL 386
            .:||..:.:.|.:||.|||..||...:      :....::....|.::...|||.::||:.:||:
  Rat   259 TKMLFVLVLVFAICWTPFHVDRLFFSF------VEEWTESLAAVFNLIHVVSGVFFYLSSAVNPI 317

  Fly   387 LYNIMSHKFREAFKITLTRQFGLARNHHHQQSQHHQHNYSALLRQNGSMRLQPASCSVNNNALEP 451
            :||::|.:||.||:..::.........|..|.                                |
  Rat   318 IYNLLSRRFRAAFRNVVSPTCKWCHPRHRPQG--------------------------------P 350

  Fly   452 YGSYRVVQFRC------RDANHQLSLQDSIRTTTTTT 482
            .....:....|      .||..|...|.||..|..||
  Rat   351 PAQKIIFLTECHLVELTEDAGPQFPGQSSIHNTNLTT 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R1	NP_731790.1	7tm_4	114..>242	CDD:304433	53/127 (42%)
PK2-R1	NP_731790.1	7tm_1	124..388	CDD:278431	89/273 (33%)
Nmur2	NP_071611.3	7tm_4	48..333	CDD:304433	99/293 (34%)
		7tm_1	54..319	CDD:278431	89/273 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	374..395		6/14 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338874
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BGH7
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380940at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8974
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24243
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X673
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.810