Protein Alignment PK2-R1 and NTSR1

DIOPT Version :9

• Sequence 1: NP_731790.1
• Gene: PK2-R1 / 41639
• FlyBaseID: FBgn0038140
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_002522.2
• Gene: NTSR1 / 4923
• HGNCID: 8039
• Length: 418
• Species: Homo sapiens
• Alignment Length: 362
• Identity: 116/362 - (32%)
• Similarity: 176/362 - (48%)
• Gaps: 60/362 - (16%)

  Fly    84 GSTNGTNASTMAADSP-----VDESLTLRTALTVCYALIFVAGVLGNLITCIVISRN---NFMHT 140
            |:.:| |||.....:|     |:..:..:..:|..|..:||.|.:||.:|...::|.   ..:.:
Human    36 GNASG-NASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQS 99

  Fly   141 ATNFYLFNLAVSDLILLVSGIPQELYN-LWYPDMYPFTDAMCIMGSVLSEMAANATVLTITAFTV 204
            ..:::|.:||:|||:.|:..:|.|||| :|....:.|.||.|.....|.:....||.|.:.:.:|
Human   100 TVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSV 164

  Fly   205 ERYIAICHPFRQHTMSKLSRAIKFIFAIWLAAFLLALPQAMQFSVVYQNE--------GYSC--T 259
            |||:||||||:..|:...||..|||.|||||:.|||:|  |.|::..||.        |..|  |
Human   165 ERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVP--MLFTMGEQNRSADGQHAGGLVCTPT 227

  Fly   260 MENDFYAHVFAVSGFIFFGGPMTAICVLYVLIGVKL------------------KRSRLLQSL-P 305
            :.......|..|:.|:.|..||..|.||..:|..||                  :.|....:: |
Human   228 IHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEP 292

  Fly   306 RRTFDANRGLNAQGRVIRMLVAVAVAFFLCWAPFHAQRLMAVYGLNLINIGISRDAFN----DYF 366
            .|......|       :|:|.||.:||.:||.|:|.:|||..|        ||.:.:.    |::
Human   293 GRVQALRHG-------VRVLRAVVIAFVVCWLPYHVRRLMFCY--------ISDEQWTPFLYDFY 342

  Fly   367 RILDYTSGVLYFLSTCINPLLYNIMSHKFREAFKITL 403
            ......:..|:::|:.|||:|||::|..||..|..||
Human   343 HYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATL 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R1	NP_731790.1	7tm_4	114..>242	CDD:304433	53/131 (40%)
		7tm_1	124..388	CDD:278431	95/300 (32%)
NTSR1	NP_002522.2	7tm_1	80..364	CDD:278431	95/300 (32%)
		7tm_4	<159..381	CDD:304433	79/238 (33%)
		Neurotensin binding. /evidence=ECO:0000250	321..344		7/30 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380940at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24243
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020