DRSC/TRiP Functional Genomics Resources

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Protein Alignment PK2-R1 and PK2-R2

DIOPT Version :10

Sequence 1:NP_731790.1 Gene:PK2-R1 / 41639 FlyBaseID:FBgn0038140 Length:660 Species:Drosophila melanogaster
Sequence 2:NP_731788.1 Gene:PK2-R2 / 41638 FlyBaseID:FBgn0038139 Length:599 Species:Drosophila melanogaster


Alignment Length:647 Identity:346/647 - (53%)
Similarity:409/647 - (63%) Gaps:124/647 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    55 EMLLLKNDKFLTHVAHLLNITTENLSNLL-GSTNGTNASTMAADSPVDESLTLRTALTVCYALIF 118
            ::.|..|:|||.::..:|||:.:||::|| |........|:...:|    |:|...|:|.|||||
  Fly    17 DLQLFHNEKFLLNLTQVLNISADNLTSLLQGLEPEELLPTVTPMTP----LSLLATLSVGYALIF 77

  Fly   119 VAGVLGNLITCIVISRNNFMHTATNFYLFNLAVSDLILLVSGIPQELYNLWYPDMYPFTDAMCIM 183
            :|||||||||||||||||||||||||||||||:||:|||.||:||:|||||:||.|||:|::||:
  Fly    78 IAGVLGNLITCIVISRNNFMHTATNFYLFNLAISDMILLCSGMPQDLYNLWHPDNYPFSDSICIL 142

  Fly   184 GSVLSEMAANATVLTITAFTVERYIAICHPFRQHTMSKLSRAIKFIFAIWLAAFLLALPQAMQFS 248
            .|||||.|||||||||||||||||||||||||||||||||||:|||||||:||.|||||||:|||
  Fly   143 ESVLSETAANATVLTITAFTVERYIAICHPFRQHTMSKLSRAVKFIFAIWIAALLLALPQAIQFS 207

  Fly   249 VVYQNEGYSCTMENDFYAHVFAVSGFIFFGGPMTAICVLYVLIGVKLKRSRLLQSLPRRTFDANR 313
            ||.|..|.||||:|||:|||||||||:|||||||||||||||||||||||||||:||||.:|.||
  Fly   208 VVMQGMGTSCTMKNDFFAHVFAVSGFLFFGGPMTAICVLYVLIGVKLKRSRLLQALPRRCYDVNR 272

  Fly   314 GLNAQGRVIRMLVAVAVAFFLCWAPFHAQRLMAVYGLNLINIGISRDAFNDYFRILDYTSGVLYF 378
            |::||.||||||||||||||:|||||||||||||||   ...||....|||.|.|||||||||||
  Fly   273 GISAQTRVIRMLVAVAVAFFICWAPFHAQRLMAVYG---STSGIESQWFNDVFSILDYTSGVLYF 334

  Fly   379 LSTCINPLLYNIMSHKFREAFKITLTRQFGLARNHHHQQSQHHQHNYSALLR-QNGSMRLQPASC 442
            ||||||||||||||||||||||:||.|.|||...:   |.:...|.||||.| |.||:||...  
  Fly   335 LSTCINPLLYNIMSHKFREAFKVTLARHFGLGGKN---QGRGLPHTYSALRRNQTGSLRLHTT-- 394

  Fly   443 SVNNNALEPYGSYRVVQFRCRDANHQLSLQDSIRTT-----TTTTTINSNSMAAGNGVGGGAGGG 502
                                          ||:|||     ||||.:|.::..:|||...|....
  Fly   395 ------------------------------DSVRTTMTSMATTTTGLNGSANGSGNGTTTGQSVR 429

  Fly   503 GG----------GRRLRKQELYGPGPGTAVPHRMLQAQVSQLSSLGDANSLLEAEVVDRHYASGR 557
            ..          |:...:|:|:..      |.||||.|:|||||:|||:||||.:          
  Fly   430 LNRVSLDSVQMQGQNRSRQDLFDN------PRRMLQTQISQLSSVGDAHSLLEED---------- 478

  Fly   558 AKRALLATKSGALLVTPPQSGDPSEVSQPA---------------TRLKLTRVISR-----RDEV 602
                         |..|   |:|.: .||.               :|||||| |:|     ...|
  Fly   479 -------------LQFP---GEPLQ-RQPTMCSIDELTDDLAISRSRLKLTR-ITRPPGGVTGGV 525

  Fly   603 ANTSTPPFCGSHSLPDPET-----------CQSASVAGRSSRKFPWRKRRQKTEDPSSEGLT 653
            |..||....||..:...|:           .:|:|.......||.||.||:.:..|..:|.|
  Fly   526 AGGSTTGAAGSGGVSGDESSGKVRKAKVKVLKSSSPFKGLRTKFNWRARRKGSHKPHEKGAT 587

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PK2-R1NP_731790.1 7tmA_capaR 108..399 CDD:320262 241/290 (83%)
TM helix 1 108..135 CDD:320262 21/26 (81%)
TM helix 2 142..168 CDD:320262 20/25 (80%)
TM helix 3 181..211 CDD:320262 26/29 (90%)
TM helix 4 223..245 CDD:320262 18/21 (86%)
TM helix 5 265..294 CDD:320262 26/28 (93%)
TM helix 6 316..346 CDD:320262 26/29 (90%)
TM helix 7 367..392 CDD:320262 23/24 (96%)
PK2-R2NP_731788.1 7tmA_capaR 69..355 CDD:320262 241/288 (84%)
TM helix 1 69..94 CDD:320262 21/24 (88%)
TM helix 2 101..127 CDD:320262 20/25 (80%)
TM helix 3 140..170 CDD:320262 26/29 (90%)
TM helix 4 182..204 CDD:320262 18/21 (86%)
TM helix 5 225..253 CDD:320262 26/27 (96%)
TM helix 6 275..305 CDD:320262 26/29 (90%)
TM helix 7 323..348 CDD:320262 23/24 (96%)

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