Protein Alignment PK2-R1 and Gpr39

DIOPT Version :10

• Sequence 1: NP_731790.1
• Gene: PK2-R1 / 41639
• FlyBaseID: FBgn0038140
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_001107864.1
• Gene: Gpr39 / 288995
• RGDID: 1306745
• Length: 456
• Species: Rattus norvegicus
• Alignment Length: 400
• Identity: 103/400 - (25%)
• Similarity: 182/400 - (45%)
• Gaps: 56/400 - (14%)

  Fly    82 LLGSTNGTNASTMAAD-SPVDE---SLTLRTALTVCYALIFVAGVLGNLIT---CIVISRNNFMH 139
            :..|:..:|..:...| |.|.|   :..::..||:.|.::||.|:|||.:|   ..|:.:..::.
  Rat     1 MASSSGSSNICSRVIDHSHVPEFEVATWIKITLTLVYLIVFVVGILGNSVTIRVTQVLQKKGYLQ 65

  Fly   140 TATNFYLFNLAVSDLILLVSGIPQELYN-LWYPDMYPFTDAMCIMGSVLSEMAANATVLTITAFT 203
            .....::.:||.||:::.:.|:|.|.|: :|.|...|.....|.:.:.|.|..:.||:|.:...:
  Rat    66 KEVTDHMISLACSDILVFLIGMPMEFYSIIWNPLTTPSYALSCKLHTFLFETCSYATLLHVLTLS 130

  Fly   204 VERYIAICHPFRQHTMSKLSRAIKFIFAIWLAAFLLALPQAMQFSVVY------QNEGYSC---- 258
            .|||||||||||...:|...:....|..:|:.:.|:|||......:.|      .::|.:|
  Rat   131 FERYIAICHPFRYKDVSGPCQVKLLIGFVWVTSALVALPLLFAMGIEYPLANVPTHKGLNCNLSR 195

  Fly   259 TMEND-------------------FYAHVF-AVSGFIFFGGPMTAICVLYVLIGVKLKRSRLLQS 303
            |..:|                   |.:.:| |.:.::.....:..:|...:.:.:|.||..|..:
  Rat   196 TRHHDHPGDSNMSICTNLSSRWEVFQSSIFGAFAVYLVVLVSVAFMCWNMMKVLMKSKRGTLAGT 260

  Fly   304 LPR---RTFDANRGLNAQGRVIRMLVAVAVAFFLCWAPFHAQRLMAVYGLNLINIGISRDAFNDY 365
            .|:   |..::.....|:.:.|..|..:.|...:||.|...:|:||.       .....|....|
  Rat   261 GPQLQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAA-------AKPKHDWTKSY 318

  Fly   366 FR---ILDYTSGVLYFLSTCINPLLYNIMSHKFREAF-KITLTRQFGLARNHHHQQSQHHQHNYS 426
            |:   ||...|...::||:.:||||||:.|.:||:.| ::...|   |...|.:|:.|...: :|
  Rat   319 FKAYMILLPFSDTFFYLSSVVNPLLYNVSSQQFRKVFWQVLCCR---LTLQHANQEKQQRAY-FS 379

  Fly   427 ALLRQNGSMR 436
            :....:.|.|
  Rat   380 STKNSSRSAR 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R1	NP_731790.1	7tmA_capaR	108..399	CDD:320262	88/330 (27%)
		TM helix 1	108..135	CDD:320262	11/29 (38%)
		TM helix 2	142..168	CDD:320262	8/26 (31%)
		TM helix 3	181..211	CDD:320262	11/29 (38%)
		TM helix 4	223..245	CDD:320262	6/21 (29%)
		TM helix 5	265..294	CDD:320262	3/29 (10%)
		TM helix 6	316..346	CDD:320262	8/29 (28%)
		TM helix 7	367..392	CDD:320262	11/27 (41%)
Gpr39	NP_001107864.1	7tmA_GPR39	31..355	CDD:320263	88/330 (27%)
		TM helix 1	31..58	CDD:320263	10/26 (38%)
		TM helix 2	68..94	CDD:320263	8/25 (32%)
		TM helix 3	108..138	CDD:320263	11/29 (38%)
		TM helix 4	150..172	CDD:320263	6/21 (29%)
		TM helix 5	217..246	CDD:320263	4/28 (14%)
		TM helix 6	276..306	CDD:320263	8/29 (28%)
		TM helix 7	323..348	CDD:320263	11/24 (46%)