Protein Alignment PK2-R1 and NTSR2

DIOPT Version :9

• Sequence 1: NP_731790.1
• Gene: PK2-R1 / 41639
• FlyBaseID: FBgn0038140
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_036476.2
• Gene: NTSR2 / 23620
• HGNCID: 8040
• Length: 410
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 97/377 - (25%)
• Similarity: 159/377 - (42%)
• Gaps: 82/377 - (21%)

  Fly   100 VDESLTLRTALTVCYALIFVAGVLGNLITCIVISR------NNFMHTATNFYLFNLAVSDLILLV 158
            ||..|..:...|..||||:..|..||.::..|:.:      ....|     ::.:||::.|:||:
Human    25 VDTRLWAKVLFTALYALIWALGAAGNALSAHVVLKARAGRAGRLRH-----HVLSLALAGLLLLL 84

  Fly   159 SGIPQELYN-LWYPDMYPFTDAMCIMGSVLSEMAANATVLTITAFTVERYIAICHPFRQHTMSKL 222
            .|:|.|||: :|:...:.|.|..|.....:.|:.|.||||::...:.||.:|:|.|.|..::...
Human    85 VGVPVELYSFVWFHYPWVFGDLGCRGYYFVHELCAYATVLSVAGLSAERCLAVCQPLRARSLLTP 149

  Fly   223 SRAIKFIFAIWLAAFLLALPQAMQFSVVYQNE---------GYSCTM------------ENDFYA 266
            .|....:...|.|:..||||.|:.....::.|         ...||:            .|...:
Human   150 RRTRWLVALSWAASLGLALPMAVIMGQKHELETADGEPEPASRVCTVLVSRTALQVFIQVNVLVS 214

  Fly   267 HVFAVSGFIFFGG----PMTAICVLYVLIGVK----------LKRSRLLQSLP-RRTF------- 309
            .|..::...|..|    .:.|:|.........          |....||..:. ::||
Human   215 FVLPLALTAFLNGVTVSHLLALCSQVPSTSTPGSSTPSRLELLSEEGLLSFIVWKKTFIQGGQVS 279

  Fly   310 -----DANRGLNAQGRVIRMLVAVAVAFFLCWAPFHAQRLMAVYGLNLINIGISRDAFND----- 364
                 |..| :.:..|.:::|.|:.|.:.:||.|:||:|||..|        :..||:.|
Human   280 LVRHKDVRR-IRSLQRSVQVLRAIVVMYVICWLPYHARRLMYCY--------VPDDAWTDPLYNF 335

  Fly   365 --YFRILDYTSGVLYFLSTCINPLLYNIMSHKFREAFKITLTRQFGLARNHH 414
              ||.::..|   |:::|:.:.|||||.:|..||:.|   |.....|...||
Human   336 YHYFYMVTNT---LFYVSSAVTPLLYNAVSSSFRKLF---LEAVSSLCGEHH 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R1	NP_731790.1	7tm_4	114..>242	CDD:304433	40/134 (30%)
		7tm_1	124..388	CDD:278431	77/325 (24%)
NTSR2	NP_036476.2	7tmA_NTSR2	33..369	CDD:320478	89/352 (25%)
		TM helix 1	33..60	CDD:320478	9/26 (35%)
		TM helix 2	68..94	CDD:320478	11/30 (37%)
		TM helix 3	108..138	CDD:320478	10/29 (34%)
		TM helix 4	152..170	CDD:320478	5/17 (29%)
		TM helix 5	203..232	CDD:320478	4/28 (14%)
		TM helix 6	290..320	CDD:320478	11/29 (38%)
		TM helix 7	337..362	CDD:320478	10/27 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	381..410		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380940at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24243
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020