Protein Alignment PK2-R1 and Ghsr

DIOPT Version :9

• Sequence 1: NP_731790.1
• Gene: PK2-R1 / 41639
• FlyBaseID: FBgn0038140
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: XP_017175002.1
• Gene: Ghsr / 208188
• MGIID: 2441906
• Length: 427
• Species: Mus musculus
• Alignment Length: 411
• Identity: 138/411 - (33%)
• Similarity: 189/411 - (45%)
• Gaps: 72/411 - (17%)

  Fly    24 AHVSP--SPNQSPSIGVGIGIASSTM--------------ANPSESPEMLLLKNDKFLTHVAHLL 72
            ||.||  :|..:|::....|....|.              |.|||.||.
Mouse    27 AHSSPHAAPRPAPTLPRLGGPPQGTRFPRGCDPKPGNMWNATPSEEPEP---------------- 75

  Fly    73 NITTENLSNLLGSTNGTNASTMAADSPVDESLTLRTA------LTVCYALIFVAGVLGNLITCIV 131
            |:|.:    |....:..|      ||..||.|.|..|      ...|.|| ||.|:.|||:|.:|
Mouse    76 NVTLD----LDWDASPGN------DSLSDELLPLFPAPLLAGVTATCVAL-FVVGISGNLLTMLV 129

  Fly   132 ISRNNFMHTATNFYLFNLAVSDLILLVSGIPQELYNLWYPDMYPFTDAMCIMGSVLSEMAANATV 196
            :||...:.|.||.||.::|.|||::.:. :|.:|..||....:.|.|.:|.:...:||....|||
Mouse   130 VSRFRELRTTTNLYLSSMAFSDLLIFLC-MPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATV 193

  Fly   197 LTITAFTVERYIAICHPFRQHTMSKLSRAIKFIFAIWLAAFLLALPQAMQFSVVYQNEGYSCTME 261
            |||||.:||||.|||.|.|...:....|....|..||..||..|.|..:...|.::| |......
Mouse   194 LTITALSVERYFAICFPLRAKVVVTKGRVKLVILVIWAVAFCSAGPIFVLVGVEHEN-GTDPRDT 257

  Fly   262 NDFYAHVFAV-SGF---------IFFGGPMTAICVLYVLIGVKLKRSRLLQSLPRRTFDANRGLN 316
            |:..|..||| ||.         :||..|:..:.|||.|||.||.|.|...::.....|.|
Mouse   258 NECRATEFAVRSGLLTVMVWVSSVFFFLPVFCLTVLYSLIGRKLWRRRGDAAVGSSLRDQN---- 318

  Fly   317 AQGRVIRMLVAVAVAFFLCWAPFHAQRLMAVYGLNLINIGISRDAFNDYFRILDYTSGVLYFLST 381
             ..:.::||..|..||.|||.|||..|.:........::.|::  .:.|..::.:   ||::||.
Mouse   319 -HKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQ--ISQYCNLVSF---VLFYLSA 377

  Fly   382 CINPLLYNIMSHKFREA-FKI 401
            .|||:||||||.|:|.| ||:
Mouse   378 AINPILYNIMSKKYRVAVFKL 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R1	NP_731790.1	7tm_4	114..>242	CDD:304433	54/127 (43%)
		7tm_1	124..388	CDD:278431	96/273 (35%)
Ghsr	XP_017175002.1	7tmA_GHSR	107..395	CDD:320259	110/300 (37%)
		TM helix 1	108..132	CDD:320259	11/24 (46%)
		TM helix 2	141..162	CDD:320259	8/21 (38%)
		TM helix 3	179..201	CDD:320259	10/21 (48%)
		TM helix 4	224..240	CDD:320259	6/15 (40%)
		TM helix 5	272..295	CDD:320259	5/22 (23%)
		TM helix 6	320..345	CDD:320259	11/24 (46%)
		TM helix 7	363..388	CDD:320259	12/27 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380940at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24243
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5416
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050