DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PK2-R1 and LOC101732366

DIOPT Version :9

Sequence 1:	NP_731790.1	Gene:	PK2-R1 / 41639	FlyBaseID:	FBgn0038140	Length:	660	Species:	Drosophila melanogaster
Sequence 2:	XP_004918724.1	Gene:	LOC101732366 / 101732366	-ID:	-	Length:	373	Species:	Xenopus tropicalis

Alignment Length:	354	Identity:	98/354 - (27%)
Similarity:	164/354 - (46%)	Gaps:	67/354 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 STMAADSPVDE--------SLTLRTALTVCYALIFVAGVLGNLITCIVI--SRNNFMHTATNFYL 146
            ||.::..||.:        |:..::::::.|.|:..||:|||.:...|:  .|...:..:.:.::
Frog     3 STTSSMPPVSKPPEAEVRLSIYAKSSISLTYMLLLFAGILGNAMVIRVLWGLRRRRVQASLSHHM 67

  Fly   147 FNLAVSDLILLVSGIPQELY-NLWYPDMYPFTDAMCIMGSVLSEMAANATVLTITAFTVERYIAI 210
            .:||..||:.||.|||.||| ::|.|..:|..:..|.....|.|:...|.:..:.:.:.||::|.
Frog    68 CSLASCDLLQLVLGIPAELYGSIWSPFPWPLGNIGCCGFYYLWEVLCYAAIFNVLSLSCERHLAT 132

  Fly   211 CHPFRQHTMSKLSRAIKFIFAIWLAAFLLALPQ--AMQFSVVY-------QNEGYSCT----MEN 262
            |.|...| :.:.|..::..| |||.:.|..||.  .|....||       ..|.:.||    .:.
Frog   133 CRPLSLH-LRQSSVRLRLCF-IWLMSLLAGLPVLFTMGLEDVYAADVDDQHTELWVCTPLSSRKG 195

  Fly   263 DFYAHVFAVSGFIFFGGPMTAICVLYVLIGVKLKRSR------------------LLQSLPRRTF 309
            .|.|.::|  .|:.:.|.::       ::|:...|.|                  .:|.|.|  |
Frog   196 LFVATIWA--SFLTYLGVLS-------VVGITCWRMRRALQGSASQDVEVAGPGGSVQLLGR--F 249

  Fly   310 DANRGLNAQGRVIRMLVAVAVAFFLCWAPFHAQRLMAVYGLNLINIGISRDAFND-YFR---ILD 370
            .:.:.:.|:.:..|||..:..|..:||.||.|:|||.|..        |:|.:.: |:|   .|.
Frog   250 CSGQTVTARKQNARMLGCIVGALAVCWLPFQARRLMTVLR--------SKDQWTENYYRSYITLQ 306

  Fly   371 YTSGVLYFLSTCINPLLYNIMSHKFREAF 399
            ..:...|:||:|:.|||||:.|..||.||
Frog   307 PITNCFYYLSSCLTPLLYNLTSQSFRRAF 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R1	NP_731790.1	7tm_4	114..>242	CDD:304433	40/130 (31%)
PK2-R1	NP_731790.1	7tm_1	124..388	CDD:278431	80/301 (27%)
LOC101732366	XP_004918724.1	7tm_GPCRs	27..335	CDD:391938	91/328 (28%)
		TM helix 1	29..53	CDD:341315	8/23 (35%)
		TM helix 2	64..86	CDD:341315	9/21 (43%)
		TM helix 3	104..126	CDD:341315	3/21 (14%)
		TM helix 4	147..163	CDD:341315	6/16 (38%)
		TM helix 5	194..217	CDD:341315	5/31 (16%)
		TM helix 6	259..284	CDD:341315	9/24 (38%)
		TM helix 7	303..328	CDD:341315	10/24 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380940at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920