DRSC/TRiP Functional Genomics Resources

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Protein Alignment PK2-R2 and Ghsr

DIOPT Version :9

Sequence 1:NP_731788.1 Gene:PK2-R2 / 41638 FlyBaseID:FBgn0038139 Length:599 Species:Drosophila melanogaster
Sequence 2:NP_114464.1 Gene:Ghsr / 84022 RGDID:621397 Length:364 Species:Rattus norvegicus


Alignment Length:325 Identity:128/325 - (39%)
Similarity:166/325 - (51%) Gaps:36/325 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 PEELLPTVTPMTPLSLLATLSVGYALIFIAGVLGNLITCIVISRNNFMHTATNFYLFNLAISD-M 113
            |:|||    |:.|..|||.::.....:|:.|:.|||:|.:|:||...:.|.||.||.::|.|| :
  Rat    30 PDELL----PLFPAPLLAGVTATCVALFVVGISGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLL 90

  Fly   114 ILLCSGMPQDLYNLWHPDNYPFSDSICILESVLSETAANATVLTITAFTVERYIAICHPFRQHTM 178
            |.||  ||.||..||....:.|.|.:|.|...:||:...||||||||.:||||.|||.|.|...:
  Rat    91 IFLC--MPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVV 153

  Fly   179 SKLSRAVKFIFAIWIAALLLALPQAIQFSVVMQGMGTSCTMKNDFFAHVFAV-SGFL-------- 234
            ....|....|..||..|...|.|..:...|..:. ||.....|:..|..||| ||.|        
  Rat   154 VTKGRVKLVILVIWAVAFCSAGPIFVLVGVEHEN-GTDPRDTNECRATEFAVRSGLLTVMVWVSS 217

  Fly   235 -FFGGPMTAICVLYVLIGVKLKRSRLLQALPRRCYDVNRGISAQTRVIRMLVAVAVAFFICWAPF 298
             ||..|:..:.|||.|||.||.|.|...|:.....|.|     ..:.::||..|..||.:||.||
  Rat   218 VFFFLPVFCLTVLYSLIGRKLWRRRGDAAVGASLRDQN-----HKQTVKMLAVVVFAFILCWLPF 277

  Fly   299 HAQR-LMAVYGSTSGIE----SQWFNDVFSILDYTSGVLYFLSTCINPLLYNIMSHKFREA-FKV 357
            |..| |.:.......:|    ||:.|.|       |.||::||..|||:||||||.|:|.| ||:
  Rat   278 HVGRYLFSKSFEPGSLEIAQISQYCNLV-------SFVLFYLSAAINPILYNIMSKKYRVAVFKL 335

  Fly   358  357
              Rat   336  335

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PK2-R2NP_731788.1 7tm_1 83..344 CDD:278431 106/276 (38%)
GhsrNP_114464.1 7tmA_GHSR 44..332 CDD:320259 116/302 (38%)
TM helix 1 45..69 CDD:320259 7/23 (30%)
TM helix 2 78..99 CDD:320259 11/22 (50%)
TM helix 3 116..138 CDD:320259 11/21 (52%)
TM helix 4 161..177 CDD:320259 5/15 (33%)
TM helix 5 209..232 CDD:320259 6/22 (27%)
TM helix 6 260..282 CDD:320259 10/21 (48%)
TM helix 7 300..325 CDD:320259 15/31 (48%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D380940at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24243
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
44.020

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