Protein Alignment PK2-R2 and ghsra

DIOPT Version :10

• Sequence 1: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_001139744.1
• Gene: ghsra / 795753
• ZFINID: ZDB-GENE-070912-238
• Length: 360
• Species: Danio rerio
• Alignment Length: 358
• Identity: 120/358 - (33%)
• Similarity: 175/358 - (48%)
• Gaps: 52/358 - (14%)

  Fly    62 PLSLLATLSVGYALIFIAGVLGNLITCIVISRNNFMHTATNFYLFNLAISD-MILLCSGMPQDLY 125
            |:.:|..::|...|.|..||.|||:|.:|:::...|.|.||.||.::|.|| :|.||  ||.|||
Zfish    33 PIPVLTGVTVTCVLFFFVGVTGNLMTILVVTKYKDMRTTTNLYLSSMAFSDLLIFLC--MPLDLY 95

  Fly   126 NLWHPDNYPFSDSICILESVLSETAANATVLTITAFTVERYIAICHPFRQHTMSKLSRAVKFIFA 190
            .:|....:.|.:.:|.|...:||....:|:|.|||.:||||.|||.|.|...:....|....|..
Zfish    96 RIWRYRPWNFGNILCKLFQFVSECCTYSTILNITALSVERYFAICFPLRAKVVVTKGRVRGVILV 160

  Fly   191 IWIAALLLALPQAIQFSVVMQGMGTSCTMKNDFFAHVFAV-SGFL---------FFGGPMTAICV 245
            :||.:...|.|..:...|..:. ||:....|:..|..:|: ||.|         ||..|:..:.|
Zfish   161 LWIVSFFSAGPVFVLVGVEHEN-GTNSWDTNECKATEYAIRSGLLTIMVWVSSIFFFLPVFCLTV 224

  Fly   246 LYVLIGVKL-KRSRLLQALPRRCYDVNRGISAQTR------VIRMLVAVAVAFFICWAPFHAQRL 303
            ||.|||.|| ||.|           ...|.:|.:|      .::||..|..||.:||.|||..|.
Zfish   225 LYSLIGRKLWKRKR-----------ETIGENASSRDKSNRQTVKMLAVVVFAFVLCWLPFHVGRY 278

  Fly   304 MAVYGSTSGIESQWFNDVFSILDY----TSGVLYFLSTCINPLLYNIMSHKFREAFKVTLARHFG 364
            :....:..|      :.|.||:.:    .|.||::||..|||:||||||.|:|.|    ..:.||
Zfish   279 LISKSTEMG------SPVMSIISHYCNLISFVLFYLSAAINPILYNIMSKKYRMA----ACKLFG 333

  Fly   365 LGGKNQGRGLPHTYSALRRNQTGSLRLHTTDSV 397
            |      |.:|...:::.:.::......:|.|:
Zfish   334 L------RNIPRRSTSVAKGESSPCWTESTASL 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R2	NP_731788.1	7tmA_capaR	69..355	CDD:320262	110/307 (36%)
		TM helix 1	69..94	CDD:320262	10/24 (42%)
		TM helix 2	101..127	CDD:320262	15/26 (58%)
		TM helix 3	140..170	CDD:320262	14/29 (48%)
		TM helix 4	182..204	CDD:320262	6/21 (29%)
		TM helix 5	225..253	CDD:320262	14/37 (38%)
		TM helix 6	275..305	CDD:320262	13/35 (37%)
		TM helix 7	323..348	CDD:320262	14/28 (50%)
ghsra	NP_001139744.1	7tm_GPCRs	38..328	CDD:475119	111/313 (35%)
		TM helix 1	40..64	CDD:410628	10/23 (43%)
		TM helix 2	73..94	CDD:410628	11/22 (50%)
		TM helix 3	111..133	CDD:410628	8/21 (38%)
		TM helix 4	156..172	CDD:410628	4/15 (27%)
		TM helix 5	204..227	CDD:410628	6/22 (27%)
		TM helix 6	256..278	CDD:410628	10/21 (48%)
		TM helix 7	296..321	CDD:410628	12/24 (50%)