Protein Alignment PK2-R2 and NMUR2

DIOPT Version :9

• Sequence 1: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_064552.3
• Gene: NMUR2 / 56923
• HGNCID: 16454
• Length: 415
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 112/309 - (36%)
• Similarity: 178/309 - (57%)
• Gaps: 38/309 - (12%)

  Fly    69 LSVGYALIFIAGVLGNLITCIVISRNNFMHTATNFYLFNLAISDMILLCSGMPQDLYNLWHPDNY 133
            :||.|..||:.||:||::.|:||.::..|.|.||:|||:||:||:::|..|||.::|.:|.  ||
Human    48 VSVVYVPIFVVGVIGNVLVCLVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWR--NY 110

  Fly   134 P--FSDSICILESVLSETAANATVLTITAFTVERYIAICHPFRQHTMSKLSRAVKFIFAIWIAAL 196
            |  |....|..::.|.||...|::|:||..:||||:||.||||....|...||::.:..:|..::
Human   111 PFLFGPVGCYFKTALFETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALRILGIVWGFSV 175

  Fly   197 LLALP----QAIQFSVVMQGM----GTSCTMKNDFFAH--VFAVSGFLFFGGPMTAICVLYVLIG 251
            |.:||    ..|:|.....|.    ..:||:....:.:  :..|:.|||:..|||.|.|||.|:.
Human   176 LFSLPNTSIHGIKFHYFPNGSLVPGSATCTVIKPMWIYNFIIQVTSFLFYLLPMTVISVLYYLMA 240

  Fly   252 VKLKRSRLLQA------LPRRCYDVNRGISAQTRVIRMLVAVAVAFFICWAPFHAQRLMAVYGST 310
            ::||:.:.|:|      :.|.|         :..|.:||..:.:.|.|||||||..||.     .
Human   241 LRLKKDKSLEADEGNANIQRPC---------RKSVNKMLFVLVLVFAICWAPFHIDRLF-----F 291

  Fly   311 SGIESQWFND---VFSILDYTSGVLYFLSTCINPLLYNIMSHKFREAFK 356
            |.:| :|...   ||:::...|||.::||:.:||::||::|.:|:.||:
Human   292 SFVE-EWSESLAAVFNLVHVVSGVFFYLSSAVNPIIYNLLSRRFQAAFQ 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R2	NP_731788.1	7tm_1	83..344	CDD:278431	99/281 (35%)
NMUR2	NP_064552.3	7tm_1	62..327	CDD:278431	99/281 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145173
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BGH7
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380940at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8501
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24243
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5416
SonicParanoid	1	1.000	-	-		X673
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.840