Protein Alignment PK2-R2 and NTSR1

DIOPT Version :9

• Sequence 1: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_002522.2
• Gene: NTSR1 / 4923
• HGNCID: 8039
• Length: 418
• Species: Homo sapiens
• Alignment Length: 381
• Identity: 115/381 - (30%)
• Similarity: 178/381 - (46%)
• Gaps: 72/381 - (18%)

  Fly    37 SADNLTSLLQGLEPEELLP-------------TVTPMTPLSL------LATLSVGYALIFIAGVL 82
            :||.......|||...|.|             ...|.:.|.:      ...::..|..:|:.|.:
Human    15 AADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTV 79

  Fly    83 GNLITCIVISRN---NFMHTATNFYLFNLAISDMILLCSGMPQDLYN-LW--HPDNYPFSDSICI 141
            ||.:|...::|.   ..:.:..:::|.:||:||::.|...||.:||| :|  ||  :.|.|:.|.
Human    80 GNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHP--WAFGDAGCR 142

  Fly   142 LESVLSETAANATVLTITAFTVERYIAICHPFRQHTMSKLSRAVKFIFAIWIAALLLALPQAIQF 206
            ....|.:....||.|.:.:.:||||:||||||:..|:...||..|||.|||:|:.|||:|  :.|
Human   143 GYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVP--MLF 205

  Fly   207 SVVMQ----------GMGTSCTMKNDFFAHVFAVSGFLFFGGPMTAICVLYVLIGVKL------- 254
            ::..|          |:..:.|:.......|..|:.|:.|..||..|.||..:|..||
Human   206 TMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQA 270

  Fly   255 -----------KRSRLLQAL-PRRCYDVNRGISAQTRVIRMLVAVAVAFFICWAPFHAQRLMAVY 307
                       :.|....|: |.|...:..|       :|:|.||.:||.:||.|:|.:|||..|
Human   271 AEQGQVCTVGGEHSTFSMAIEPGRVQALRHG-------VRVLRAVVIAFVVCWLPYHVRRLMFCY 328

  Fly   308 GSTSGIESQWFNDVFSILDY---TSGVLYFLSTCINPLLYNIMSHKFREAFKVTLA 360
            .|    :.||...::....|   .:..|:::|:.|||:|||::|..||..|..|||
Human   329 IS----DEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLA 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R2	NP_731788.1	7tm_1	83..344	CDD:278431	93/298 (31%)
NTSR1	NP_002522.2	7tm_1	80..364	CDD:278431	93/298 (31%)
		7tm_4	<159..381	CDD:304433	78/235 (33%)
		Neurotensin binding. /evidence=ECO:0000250	321..344		7/26 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380940at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24243
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020