Protein Alignment PK2-R2 and Trhr

DIOPT Version :10

• Sequence 1: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_038724.1
• Gene: Trhr / 22045
• MGIID: 98824
• Length: 393
• Species: Mus musculus
• Alignment Length: 418
• Identity: 112/418 - (26%)
• Similarity: 185/418 - (44%)
• Gaps: 82/418 - (19%)

  Fly    56 TVTPM--TPLSLLATLSVGYALIFI--------AGVLGNLITCIVISRNNFMHTATNFYLFNLAI 110
            ||:.|  |.|...|.:::.|.::.|        .|::||::..:|:.|...|.|.||.||.:||:
Mouse     5 TVSEMNQTELQPQAAVALEYQVVTILLVVIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAV 69

  Fly   111 SD-MILLCSGMP---QDLYNLWHPDNYPFSDSICILESVLSETAANATVLTITAFTVERYIAICH 171
            :| |:|:.:|:|   ..:|..|   .|.:...:||  :.|.....||:..:|||||:||||||||
Mouse    70 ADLMVLVAAGLPNITDSIYGSW---VYGYVGCLCI--TYLQYLGINASSCSITAFTIERYIAICH 129

  Fly   172 PFRQHTMSKLSRAVKFIFAIW----IAALLLALPQAIQFSVVMQGMGTSCTMK--NDFFAHVFAV 230
            |.:...:...|||.|.|..:|    |..:|......:..|.....:..||..|  .::::.::.:
Mouse   130 PIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKNAVVVSCGYKISRNYYSPIYLM 194

  Fly   231 SGFLFFGGPMTAICVLYVLIGVKLKRSRLLQALP--------------------------RRCYD 269
            ...:|:..||....|||..|.    |...|..:|                          .||:
Mouse   195 DFGVFYVVPMILATVLYGFIA----RILFLNPIPSDPKENSKMWKNDSIHQNKNLNLNATNRCF- 254

  Fly   270 VNRGISAQTRVIRMLVAVAVAFFICWAPFHAQRLMAVYGS--TSGIESQWFNDVFSILDYTSGVL 332
             |..:|::.:|.:||..|.:.|.:.|.|:   |.:.|..|  :|..:..||            :|
Mouse   255 -NSTVSSRKQVTKMLAVVVILFALLWMPY---RTLVVVNSFLSSPFQENWF------------LL 303

  Fly   333 Y-----FLSTCINPLLYNIMSHKFREAFKVTLARHFGLGGKNQGRGLPHTYSALRRNQTGSLRLH 392
            :     :|::.|||::||:||.|||.||:...........|.....:...||.::.:...|..|
Mouse   304 FCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKAANYSVALNYSVIKESDRFSTEL- 367

  Fly   393 TTDSVRTTMTSMATTTTGLNGSANGSGN 420
              :.:..|.|.::||....:.:...|.|
Mouse   368 --EDITVTDTYVSTTKVSFDDTCLASEN 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R2	NP_731788.1	7tmA_capaR	69..355	CDD:320262	93/336 (28%)
		TM helix 1	69..94	CDD:320262	6/32 (19%)
		TM helix 2	101..127	CDD:320262	12/29 (41%)
		TM helix 3	140..170	CDD:320262	15/29 (52%)
		TM helix 4	182..204	CDD:320262	8/25 (32%)
		TM helix 5	225..253	CDD:320262	7/27 (26%)
		TM helix 6	275..305	CDD:320262	9/29 (31%)
		TM helix 7	323..348	CDD:320262	7/29 (24%)
Trhr	NP_038724.1	7tmA_TRH-R	26..331	CDD:320126	92/330 (28%)
		TM helix 1	27..53	CDD:320126	5/25 (20%)
		TM helix 2	60..85	CDD:320126	11/24 (46%)
		TM helix 3	98..128	CDD:320126	15/31 (48%)
		TM helix 4	141..162	CDD:320126	7/20 (35%)
		TM helix 5	188..217	CDD:320126	7/32 (22%)
		TM helix 6	259..289	CDD:320126	10/32 (31%)
		TM helix 7	299..324	CDD:320126	9/36 (25%)