Protein Alignment PK2-R2 and nmur-1

DIOPT Version :10

• Sequence 1: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_509515.3
• Gene: nmur-1 / 183574
• WormBaseID: WBGene00016747
• Length: 400
• Species: Caenorhabditis elegans
• Alignment Length: 352
• Identity: 118/352 - (33%)
• Similarity: 178/352 - (50%)
• Gaps: 41/352 - (11%)

  Fly    73 YALIFIAGVLGNLITCIVISRNNFMHTATNFYLFNLAISDMILLCSGMPQDLYNLWHPDNYPFSD 137
            |..||:.||:||..||:|:.::..|.|..:.||.|||:||::.||.|:|.::...|:...:||.|
 Worm    58 YIFIFLVGVIGNTTTCLVMKKHPMMKTHASMYLMNLAVSDLVTLCVGLPFEVMMNWNQYPWPFPD 122

  Fly   138 SICILESVLSETAANATVLTITAFTVERYIAICHPFRQHTMSKLSRAVKFIFAI-WIAALLLALP 201
            .||.|:::::||.::.::|||..|.:|||:|:|||.....:....|.:..|... ||.::|.|:|
 Worm   123 YICNLKALIAETTSSVSILTILIFAIERYVAVCHPLFLMKVQPFKRNIGTIIGFTWIFSILCAMP 187

  Fly   202 QAIQFS---VVMQGMGTS----------CTMKNDF-------FAHVFAVSGFLFFGGPMTAICVL 246
            .||...   ::....||.          |.:...|       |..:|..|...||..|:..|.:|
 Worm   188 FAIHHRADYIMKSWPGTDNRIPVKSSKMCMIAVMFEPKLASTFKILFHFSAIAFFALPLFTIVIL 252

  Fly   247 YVLIGVKLKRSRLLQALPRRCYDVNRGISAQTRVIRMLVAVAVAFFICWAPFHAQRLMAVYGSTS 311
            |..|..|:..:|.:|  |.. .|:...:  |.|:..:|.|:..|||||:.||..|||:..|....
 Worm   253 YARIACKVSSNRTIQ--PGE-LDITEEL--QMRINAILCAIVSAFFICYLPFQLQRLLFFYFDNE 312

  Fly   312 GIESQWFNDVFSILDYTSGVLYFLSTCINPLLYNIMSHKFREAFKVTLARHFGLGGKNQ------ 370
            .|.: |.|   ..:.:.||.|::|:|.|||:.||:.|.:||.|||..|..:...||..:
 Worm   313 VILT-WVN---QYMYFISGFLFYLATIINPIAYNLASSRFRRAFKDILIDYCWRGGSERYPRSSF 373

  Fly   371 -GRGLPHTYSALRRNQTGSLRLHTTDS 396
             ...|.||  .||  |..|.|:...||
 Worm   374 SKYSLAHT--PLR--QAMSNRVPILDS 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R2	NP_731788.1	7tmA_capaR	69..355	CDD:320262	102/302 (34%)
		TM helix 1	69..94	CDD:320262	10/20 (50%)
		TM helix 2	101..127	CDD:320262	11/25 (44%)
		TM helix 3	140..170	CDD:320262	12/29 (41%)
		TM helix 4	182..204	CDD:320262	7/22 (32%)
		TM helix 5	225..253	CDD:320262	9/27 (33%)
		TM helix 6	275..305	CDD:320262	14/29 (48%)
		TM helix 7	323..348	CDD:320262	10/24 (42%)
nmur-1	NP_509515.3	7tmA_NTSR-like	52..352	CDD:320110	102/302 (34%)
		TM helix 1	52..79	CDD:320110	10/20 (50%)
		TM helix 2	86..112	CDD:320110	11/25 (44%)
		TM helix 3	125..155	CDD:320110	12/29 (41%)
		TM helix 4	168..190	CDD:320110	7/21 (33%)
		TM helix 5	230..259	CDD:320110	10/28 (36%)
		TM helix 6	276..306	CDD:320110	14/31 (45%)
		TM helix 7	320..345	CDD:320110	10/24 (42%)