Protein Alignment PK2-R2 and trhr-1

DIOPT Version :9

• Sequence 1: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_491990.1
• Gene: trhr-1 / 183056
• WormBaseID: WBGene00016265
• Length: 395
• Species: Caenorhabditis elegans
• Alignment Length: 400
• Identity: 123/400 - (30%)
• Similarity: 193/400 - (48%)
• Gaps: 63/400 - (15%)

  Fly    50 PEELLPTVTPMTPLSLLATLSVGYALIFIAGVLGNLITCIVISRNNFMHTATNFYLFNLAISDMI 114
            ||||..|:.|:....:..||:..::.|.:.||||||:...|:.:...|.|.||.||.:||.||.:
 Worm    16 PEELDGTIAPIGTQPMDITLAFVFSAISVIGVLGNLLVITVVLKVRGMKTPTNCYLVSLAASDTL 80

  Fly   115 LLCSGMPQDLYNLWHP-DNYPFSDSICILESVLSETAANATVLTITAFTVERYIAICHPFRQHTM 178
            ...:.||.::..|..| |:|.|....|:|.:.|...|.|.:.|:|.|||:|||..||:|::..||
 Worm    81 FFFASMPHEMMYLLGPNDHYLFGSLGCVLLTYLPYLAMNTSSLSILAFTIERYYGICNPYKARTM 145

  Fly   179 SKLSRAVKFIFAIWIAALLLALPQAIQFSVVMQGMGTSCTMKNDFFAH----VFAVSGFLFFGGP 239
            ..:.||...|..|||.::|.........:::...:||||:.:.:..:|    ||.:...|::..|
 Worm   146 CTVKRATCIICGIWIFSMLYHSYWLFLATLIKDDIGTSCSFRLERNSHAYKIVFLLDFVLWYVLP 210

  Fly   240 MTAICVLYVLIGV-------KLKRSRLLQALPRRCYDVNRGISAQT------------------- 278
            :....::|..||:       |:|:| :...:|.... |.:..::.|
 Worm   211 IMCDIIIYAKIGITLSQCGDKIKKS-VKPKIPNEVI-VEKSKTSSTSMGHYSGRDSHISGKRNSA 273

  Fly   279 ----RVIRMLVAVAVAFFICWAPFHAQRLMAVYGS-TSGIESQWFNDVFSILDYTSGVLYFLSTC 338
                :|::||..|...|.:||.|:   |.|.||.| .|..:..|..|.:..|..|   |.|::..
 Worm   274 KGRNQVVKMLAIVVAVFAVCWLPY---RGMVVYNSFVSDPKYSWSPDWYINLSKT---LVFINCA 332

  Fly   339 INPLLYNIMSHKFREAFKVTLARHFGLGGKNQGRGLPHTYSALRRNQTGSLRLHTTDSVRTT--- 400
            |||:|||:||.:||.||:..|::.     ||.|      :.:...||..  ||:|.|.:.:.
 Worm   333 INPILYNLMSARFRAAFRSLLSKR-----KNSG------FKSTALNQRH--RLNTMDIMSSAEPK 384

  Fly   401 ---MTSMATT 407
               :||||.|
 Worm   385 SPLITSMAGT 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R2	NP_731788.1	7tm_1	83..344	CDD:278431	87/296 (29%)
trhr-1	NP_491990.1	7tmA_TRH-R	33..349	CDD:320126	100/323 (31%)
		TM helix 1	35..59	CDD:320126	9/23 (39%)
		TM helix 2	68..90	CDD:320126	9/21 (43%)
		TM helix 3	108..130	CDD:320126	8/21 (38%)
		TM helix 4	153..169	CDD:320126	5/15 (33%)
		TM helix 5	196..219	CDD:320126	4/22 (18%)
		TM helix 6	277..302	CDD:320126	10/27 (37%)
		TM helix 7	317..342	CDD:320126	11/27 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I2906
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.960