Protein Alignment PK2-R2 and C24B5.1

DIOPT Version :9

• Sequence 1: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_505381.2
• Gene: C24B5.1 / 179301
• WormBaseID: WBGene00016044
• Length: 427
• Species: Caenorhabditis elegans
• Alignment Length: 411
• Identity: 87/411 - (21%)
• Similarity: 147/411 - (35%)
• Gaps: 97/411 - (23%)

  Fly    20 LFHNEKFLLNLTQVLNISADNLTSLLQGLEPEELL----------PTVTPMTPLSLLATLSVGYA 74
            |:|:    ||.:......|.|.||:.|.||.:...          |.:......||:..|...|.
 Worm    22 LYHH----LNASLEAAKDAVNATSVKQILEAQTHYLFNDTIFGPSPAMESTPGRSLIQNLYYFYM 82

  Fly    75 --LIFIAGVLGNLITCIVISRNNFMH-TATNFYLFNLAISDMILLCSGMP---QDLYNLWHPDNY 133
              .:|: |:.||.:..|:|..|..:: ..||.||..||....|.|.|.:.   :::..::..|
 Worm    83 PFCVFV-GLTGNTMVWILIRSNRMLNKLPTNVYLLCLAAMSSIFLLSLLVFWIEEVAYIYFYD-- 144

  Fly   134 PFSDSI-------CILESVLSETAANATVLTITAFTVERYIAICHPFRQHTMSKLSRAVKFI--- 188
            .|.||:       ||..:.|:.....|:|..|....:||.:.:....|..|..| :||..||
 Worm   145 IFQDSLLRNSYYSCIFNTFLAHVCDFASVWLIVLVGLERLLLLYRKTRGLTCEK-ARAQVFILLG 208

  Fly   189 FAI----WIAALLLALPQAIQFSVVMQGMGTSCTMKNDF---FAHVFAVSGFLFFGGP----MTA 242
            ||:    ||.           |...|...| .|.:|.:|   :..:..|...:....|    :|.
 Worm   209 FAMVFNGWIL-----------FVADMDEEG-QCDIKIEFVGMYQTMTIVETIICMLVPSVLIITC 261

  Fly   243 ICVLYVLIGVKLKRSRLLQALPRRCYDV---------NRGISAQTRV------------------ 280
            .|::...:...:|::....|:.....||         :..:.:.||:
 Worm   262 NCLVVSKLNSHIKKNPGSPAVSFNTADVVLTTQTSAPSATLKSYTRISSRFSIDVEKAPKKKKKG 326

  Fly   281 --------IRMLVAVAVAFFICWAPFHAQRLMAVYGSTSGIESQWFNDVFSILDYTSGVLYFLST 337
                    .|.|:.|..||.:...|.:..|:.::   ..||..|  :.:.:.:...:.|..:...
 Worm   327 IRYTDIQLTRSLLVVTWAFILLNIPNYGYRIASI---LFGISEQ--SSLMTAISLGAHVFLYTHH 386

  Fly   338 CINPLLYNIMSHKFREAFKVT 358
            .....||...|.:.:...|.|
 Worm   387 AFLFYLYIFYSPQMKRRLKPT 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R2	NP_731788.1	7tm_1	83..344	CDD:278431	64/320 (20%)
C24B5.1	NP_505381.2	7tm_GPCRs	77..404	CDD:391938	71/347 (20%)
		TM helix 1	77..103	CDD:341315	8/26 (31%)
		TM helix 2	111..140	CDD:341315	9/28 (32%)
		TM helix 3	158..185	CDD:341315	8/26 (31%)
		TM helix 4	197..217	CDD:341315	7/20 (35%)
		TM helix 5	239..264	CDD:341315	3/24 (13%)
		TM helix 6	329..359	CDD:341315	7/29 (24%)
		TM helix 7	372..397	CDD:341315	3/24 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24243
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010