Protein Alignment PK2-R2 and Trhr2

DIOPT Version :10

• Sequence 1: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_573465.1
• Gene: Trhr2 / 170732
• MGIID: 2177284
• Length: 382
• Species: Mus musculus
• Alignment Length: 368
• Identity: 101/368 - (27%)
• Similarity: 160/368 - (43%)
• Gaps: 75/368 - (20%)

  Fly    63 LSLLATLSVGYALIFIAGVLGNLITCIVISRNNFMHTATNFYLFNLAISDMI-LLCSGMPQDLYN 126
            :|:|..|     |:...|::||.:..:|:..:..|||.||.||.:||::|:| ||.:|:|.
Mouse    24 VSVLLVL-----LVCTVGIVGNAMVVLVVLTSRDMHTPTNCYLVSLALADLIVLLAAGLPN---- 79

  Fly   127 LWHPDNYPFSDSI----------CILESVLSETAANATVLTITAFTVERYIAICHPFRQHTMSKL 181
                    .|||:          |:..:.......|.:..:|.|||||||||||||.|..|:..:
Mouse    80 --------VSDSLVGHWIYGHAGCLGITYFQYLGINVSSCSILAFTVERYIAICHPMRAQTVCTV 136

  Fly   182 SRAVKFIFAIWIAALLLALPQAIQFSVV------MQGMGTSCTMKNDFFAHVFAVSGFLFFGGPM 240
            :||.:.|..||....|..|   :.|.:|      .|.:.....:....:..::.:...:||..|:
Mouse   137 ARARRIIAGIWGVTSLYCL---LWFFLVDLNVRDNQRLECGYKVSRGLYLPIYLLDFAVFFIAPL 198

  Fly   241 TAICVLYVLIGVKLKRSRLLQ--------------ALPRRCYDVNRGISAQTRVIRMLVAVAVAF 291
            ....|||..||..|.:|.|.|              ..|..|......:|::.:..|||..:.:.|
Mouse   199 LGTLVLYGFIGRILFQSPLSQEAWQKERQSHGQSEGTPGNCSRSKSSMSSRKQATRMLAVIVLLF 263

  Fly   292 FICWAPFHAQRLMAVYGSTSGIESQWFNDVFSILDYTSGVLYFLSTC------INPLLYNIMSHK 350
            .:.|.|:....|:..:.:...:: .|             ||.|..||      |||::|::||.|
Mouse   264 AVLWTPYRTLVLLNSFLARPFLD-PW-------------VLLFCRTCVYTNSAINPVIYSLMSQK 314

  Fly   351 FREAF-KVTLARHFGLGGKNQGRGLP-HTYSALRRNQTGSLRL 391
            ||.|| |:...|  ..|.:.:....| ..|||.:....|:.::
Mouse   315 FRAAFLKLCWCR--AAGSQRRAACAPTSNYSAAQETSLGTEKM 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R2	NP_731788.1	7tmA_capaR	69..355	CDD:320262	89/322 (28%)
		TM helix 1	69..94	CDD:320262	6/24 (25%)
		TM helix 2	101..127	CDD:320262	12/26 (46%)
		TM helix 3	140..170	CDD:320262	12/29 (41%)
		TM helix 4	182..204	CDD:320262	7/21 (33%)
		TM helix 5	225..253	CDD:320262	8/27 (30%)
		TM helix 6	275..305	CDD:320262	8/29 (28%)
		TM helix 7	323..348	CDD:320262	9/30 (30%)
Trhr2	NP_573465.1	7tmA_TRH-R	33..319	CDD:320126	87/314 (28%)
		TM helix 2	57..82	CDD:320126	12/36 (33%)
		TM helix 3	95..125	CDD:320126	12/29 (41%)
		TM helix 4	138..159	CDD:320126	7/23 (30%)
		TM helix 5	182..211	CDD:320126	8/28 (29%)
		TM helix 6	214..277	CDD:320126	13/62 (21%)
		TM helix 7	287..312	CDD:320126	10/37 (27%)