Protein Alignment PK2-R2 and LOC116412424

DIOPT Version :10

• Sequence 1: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: XP_031762492.1
• Gene: LOC116412424 / 116412424
• XenbaseID: XB-GENE-29098791
• Length: 454
• Species: Xenopus tropicalis
• Alignment Length: 427
• Identity: 116/427 - (27%)
• Similarity: 187/427 - (43%)
• Gaps: 78/427 - (18%)

  Fly    23 NEKFLLNLTQVLNISADNLTSLLQGLEPEELLPTVTPMTPLSLLATLSVGYALIFIAGVLGNLIT 87
            ||. |.|.:...|:|.:.:..|..|.:.:|         |..:....::.|:|:|..|::.|.::
 Frog    20 NES-LWNESMTSNVSVETVHHLFIGAQRQE---------PNHIAIPATIFYSLLFFFGIMANGLS 74

  Fly    88 CIVISRNNFMH-TATNFYLFNLAISDMILLCSGMPQDLYN-LWHPDNYPFSDSICILESVLSETA 150
            .:.:.||..|. :|..|||.:||::|::||.: :|..||. .|....:..||.:|.|..::.:..
 Frog    75 ILTLMRNGRMKVSAVRFYLLSLAMADILLLLT-IPITLYRYFWQYYPWALSDIVCKLYFMIRQVY 138

  Fly   151 ANATVLTITAFTVERYIAICHPFRQHTMSKLSRAVKFIFAIWIAALLLALPQAIQF----SVVMQ 211
            ...|..||.|||.|||||||||....|..:.:|....:..||:.::|..:|.||.:    :.::.
 Frog   139 CATTSWTIIAFTSERYIAICHPMWSITGLRKTRMAYLLAFIWLLSILTTIPVAIVYGESSACILD 203

  Fly   212 GMGTS----------CTMKND----FFAHVFAVSGFLFFGGPMTAICVLYVLIGVKLKRSRLLQA 262
            ...||          |.|...    .:..:......|||..|:.||.:.::||...|.    |..
 Frog   204 YTATSQEEAVLDSTVCEMLEPKPYIVYKSIMQTRSILFFVMPLLAIIIFHILIFHHLS----LNQ 264

  Fly   263 LPRRCYDVN---------------RGISAQTRVIRMLVAVAVAFFICWAPFHAQRLMAVYGSTSG 312
            ..|....:|               |...::.:..:::.||.||||:|..|..|..||.:|
 Frog   265 RQREKIGLNGTHWHFSSTHANQPQRHPFSEKKARQLMGAVVVAFFLCNFPDTASSLMQIY----- 324

  Fly   313 IESQWFNDVFSIL----DYTSGVLYFLSTCINPLLYNIMSHKFREAFKVTLARHF--------GL 365
            ||: |...|:.:.    .|.|..|::|::.::|:|:.|.|..||.|...||....        |.
 Frog   325 IEN-WNAHVYKVYTWLKTYLSLPLWYLNSALDPILFCISSTSFRSACWETLTTFIPWYEKSLDGP 388

  Fly   366 GGKNQGRGLPHTYSALRRNQTGSLRLHTTDSVRTTMT 402
            |..||.       |.:|   :|...|.:..|.|:|.|
 Frog   389 GNTNQA-------SCVR---SGVSSLVSAPSTRSTWT 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R2	NP_731788.1	7tmA_capaR	69..355	CDD:320262	91/324 (28%)
		TM helix 1	69..94	CDD:320262	5/24 (21%)
		TM helix 2	101..127	CDD:320262	11/26 (42%)
		TM helix 3	140..170	CDD:320262	13/29 (45%)
		TM helix 4	182..204	CDD:320262	5/21 (24%)
		TM helix 5	225..253	CDD:320262	8/27 (30%)
		TM helix 6	275..305	CDD:320262	10/29 (34%)
		TM helix 7	323..348	CDD:320262	7/28 (25%)
LOC116412424	XP_031762492.1	7tm_GPCRs	54..369	CDD:475119	91/325 (28%)
		TM helix 1	56..80	CDD:320110	5/23 (22%)
		TM helix 2	90..112	CDD:320110	9/22 (41%)
		TM helix 3	129..151	CDD:320110	6/21 (29%)
		TM helix 4	174..190	CDD:320110	3/15 (20%)
		TM helix 5	231..264	CDD:320110	10/36 (28%)
		TM helix 6	298..320	CDD:320110	9/21 (43%)
		TM helix 7	337..363	CDD:320110	7/25 (28%)