Protein Alignment PK2-R2 and NMUR1

DIOPT Version :9

• Sequence 1: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_006047.3
• Gene: NMUR1 / 10316
• HGNCID: 4518
• Length: 426
• Species: Homo sapiens
• Alignment Length: 384
• Identity: 131/384 - (34%)
• Similarity: 197/384 - (51%)
• Gaps: 56/384 - (14%)

  Fly    34 LNISADNLTSLLQGLEPEELLPTVTPMTPLSLLATLSVGYALIFIAGVLGNLITCIVISRNNFMH 98
            ||::.:.|.....|.:..||.        :.:.||    |.|||:.|.:||.:||:||.|:..|.
Human    40 LNLTDEALRLKYLGPQQTELF--------MPICAT----YLLIFVVGAVGNGLTCLVILRHKAMR 92

  Fly    99 TATNFYLFNLAISDMILLCSGMPQDLYNLWHPDNYPFSDSI--CILESVLSETAANATVLTITAF 161
            |.||:|||:||:||:::|..|:|.:||.:||  ||||...:  |...::|.|....|:||.:||.
Human    93 TPTNYYLFSLAVSDLLVLLVGLPLELYEMWH--NYPFLLGVGGCYFRTLLFEMVCLASVLNVTAL 155

  Fly   162 TVERYIAICHPFRQHTMSKLSRAVKFIFAIWIAALLLALPQAI-----QFSVVMQGM---GTSCT 218
            :||||:|:.||.:..:|...:...:.:.|:|..|:|.:||...     |..|..:|.   ...|.
Human   156 SVERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCM 220

  Fly   219 M--KNDFFAHVFAVSGFLFFGGPMTAICVLYVLIGVKLKRSRLL---------QALPRRCYDV-- 270
            :  ....:..|...:..|||..||..:.|||:|||::|:|.|||         .|..|..|..
Human   221 LVRPRALYNMVVQTTALLFFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRL 285

  Fly   271 ---NRGISAQTRVIRMLVAVAVAFFICWAPFHAQRLMAVYGSTSGIESQWFNDV---FSILDYTS 329
               :||   :.:|.:||..:.|.|.||||||||.|:|      ..:.|||.:.:   |..:...|
Human   286 QQHDRG---RRQVTKMLFVLVVVFGICWAPFHADRVM------WSVVSQWTDGLHLAFQHVHVIS 341

  Fly   330 GVLYFLSTCINPLLYNIMSHKFREAFKVTLARHFGLGGKNQGRGLPHTYSALRRNQTGS 388
            |:.::|.:..||:||::||.:|||.|:..|.    ||.........|:..:|.|..|||
Human   342 GIFFYLGSAANPVLYSLMSSRFRETFQEALC----LGACCHRLRPRHSSHSLSRMTTGS 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R2	NP_731788.1	7tm_1	83..344	CDD:278431	101/289 (35%)
NMUR1	NP_006047.3	7tm_1	77..356	CDD:278431	101/289 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145172
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BGH7
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380940at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8501
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24243
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5416
SonicParanoid	1	1.000	-	-		X673
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.840