Protein Alignment CG32473 and LAP2

DIOPT Version :9

• Sequence 1: NP_731787.1
• Gene: CG32473 / 41636
• FlyBaseID: FBgn0052473
• Length: 1025
• Species: Drosophila melanogaster
• Sequence 2: NP_014353.1
• Gene: LAP2 / 855682
• SGDID: S000004990
• Length: 671
• Species: Saccharomyces cerevisiae
• Alignment Length: 672
• Identity: 144/672 - (21%)
• Similarity: 267/672 - (39%)
• Gaps: 173/672 - (25%)

  Fly   114 VPTSKKSSIMATVAPAVKAAS--KVL-----QNLGFRLPK--QIKPSKYR--------LHLRPDL 161
            :||.:...::..::..:..::  |:|     |....|.|:  |...|.|:        |:|....
Yeast    16 LPTLRFRGLLTVISRNIHISTPHKMLPLSIEQRRPSRSPEYDQSTLSNYKDFAVLHTDLNLSVSF 80

  Fly   162 ERKNYSGNISISLQVLEPIAFIPVHVKQ-------LNVSTVEVKRLDESGAPLKDITPTLTFAHP 219
            |:...||:::..|:.|        |..:       |:.|.::|:.:...|:
Yeast    81 EKSAISGSVTFQLKKL--------HEGKNKSDELHLDTSYLDVQEVHIDGS-------------- 123

  Fly   220 EFEYWVTEFEQPLEA----GNYSLLLNFTGSL----VDRITGMYQSSYLDKLKNR-SRSIISTKF 275
            :.::.:.:.::||.:    .|.|...|||.::    .|:.|.:   .:|:..:.: .:..:.::.
Yeast   124 KADFQIEQRKEPLGSRLVINNASCNDNFTLNIQFRTTDKCTAL---QWLNSKQTKGGKPYVFSQL 185

  Fly   276 EPTYARQAFPCFDEPALKAQFTITVARPSGDEYHVLSNMPVA-----SEYVDGDITEVTFAETVP 335
            |..:||..|||||.|::|:.||.::..|          :||.     .|....|.....|.:.||
Yeast   186 EAIHARSLFPCFDTPSVKSTFTASIESP----------LPVVFSGIRIEDTSKDTNIYRFEQKVP 240

  Fly   336 MSTYLAAFVVSDFQYKETTVEGTSIALKVYAPPAQVEKTQYA--------LDTAAGVMAYYINYF 392
            :..||......|..........|     ||..|.:::..|:.        :.||..::   ..|.
Yeast   241 IPAYLIGIASGDLSSAPIGPRST-----VYTEPFRLKDCQWEFENDVEKFIQTAEKII---FEYE 297

  Fly   393 NVSYALPKLDLVAIPDFVSGAMENWGLVTFRETALLYDESTSSSVNKQRVAIVVAHELAHQWFGN 457
            ..:|.:    ||.:..:..|.||:..:.....|.:.:|.|...         |:||||||.|.||
Yeast   298 WGTYDI----LVNVDSYPYGGMESPNMTFATPTLIAHDRSNID---------VIAHELAHSWSGN 349

  Fly   458 LVTMNWWNDLWLNEGFASFLEYKGVKQMHPE----------W-DMDNQFVIEELHPVLTIDATLA 511
            |||...||..|||||:..:||.:.:..:|.|          | |:.|           :||:  .
Yeast   350 LVTNCSWNHFWLNEGWTVYLERRIIGAIHGEPTRHFSALIGWSDLQN-----------SIDS--M 401

  Fly   512 SHP-----IVKSIESPAEITEYFDTITYSKGAALVRMLENLVGEEKLRNATTRYLVRHIYSTATT 571
            ..|     :|:::....:..:.|.|:.|.||..|:..||.::|.:    |.....:||.:.....
Yeast   402 KDPERFSTLVQNLNDNTDPDDAFSTVPYEKGFNLLFHLETILGGK----AEFDPFIRHYFKKFAK 462

  Fly   572 EDYLTAVEEEEGLEF--DVKQIM-----QTWTEQMGLP-----VVEVEKSGSTYKLTQK-----R 619
            :...|....:...||  :.|:|:     :||..:.|:|     :..:  :.:.|:|..|     :
Yeast   463 KSLDTFQFLDTLYEFYPEKKEILDSVDWETWLYKPGMPPRPHFITAL--ADNVYQLADKWVEMAQ 525

  Fly   620 FLANEDDYAAEAEA---SSFNYRWSIPITYTSSINSEVQSLIFNHNDNEATITLPEEASWIKI-- 679
            .|...:|:.:|..|   ..||         ::.:...:::|..|.:.|:.    |::..|.|.
Yeast   526 HLKTTEDFRSEFNAIDIKDFN---------SNQLVLFLETLTQNGHSNKK----PKDFDWAKFPV 577

  Fly   680 -NTNQVGYYRVNYGSEQWAELI 700
             :...:..|:.|....|.||::
Yeast   578 ASRALLDIYQDNIVKSQNAEVV 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32473	NP_731787.1	Peptidase_M1	143..537	CDD:279741	101/448 (23%)
		M1_APN_2	151..602	CDD:189008	115/510 (23%)
		ERAP1_C	677..992	CDD:288671	6/27 (22%)
LAP2	NP_014353.1	leuko_A4_hydro	57..669	CDD:274120	137/631 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810